Help!!!

[Heather234]

Hi everyone. Just reaching out to see what you all think about these lab values. Any help is help!!!!:)

Tissue transglutaminase Ab, Iga: <1.0

Immunoglobulin A: 95 

Thank you!!!

[trents]

Heather, welcome to the forum!

We can't answer your question without reference ranges for what is negative vs. positive. There are no industry standards for these parameters so every lab uses different reference ranges. Do you have that info?

[Heather234]

Thank you! 
 

The reference ranges are 

<15.0 Antibody not detected 

>15.0 Antibody detected 

And 

47-310 mg/dL

 

 

[trents]

Had you already started eating gluten free prior to the antibody test?

[Heather234]

I had not 

[trents]

Have you considered NCGS (Non Celiac Gluten Sensitivity)? It shares many of the same symptoms with celaic disease but does not damage the small bowel villi, so there are not antibodies produced to detect. It is 10-12x more common than celiac disease. The antidote is the same, avoidance of all gluten. Some experts consider it to be a precursor to celiac disease. There are no tests for NCGS. Celiac disease must first be ruled out.

Edited May 25, 2022 by trents

[Scott Adams]

It looks like a negative celiac disease test, but as @trents mentioned, would not rule out NCGS. If you go this test done due to unexplained symptoms, you may still want to try a gluten-free diet for a few weeks or months to see if it helps with your symptoms. If you have no symptoms and you have this negative test, you likely don't need to worry about gluten.

[Sabaarya]

10 hours ago, Scott Adams said:

It looks like a negative celiac disease test, but as @trents mentioned, would not rule out NCGS. If you go this test done due to unexplained symptoms, you may still want to try a gluten-free diet for a few weeks or months to see if it helps with your symptoms. If you have no symptoms and you have this negative test, you likely don't need to worry about gluten.

Hi. My whole celiac panel was absolutely in normal range but my biopsy came back positive for mild damage from celiac disease. Next my doctor ordered genetic test and it came back positive as well. So positive biopsy and genetic test was consistent with Celiac disease. Even though my GI said it’s not common for celiac patients to have negative antibodies but my son’s GI said that recently they see more and more normal antibodies in celiac patients but positive biopsies from small intestine. So probably you will need endoscopy to rule out celiac disease…

12 hours ago, Heather234 said:

Thank you! 
 

The reference ranges are 

<15.0 Antibody not detected 

>15.0 Antibody detected 

And 

47-310 mg/dL