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New Therapy For Celiac

Claire

By Claire
in Related Issues & Disorders

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Claire Collaborator
Claire
Posted

For consideration - Claire

NEW THERAPY MAY MEAN LESS DIETARY RESTRICTIONS FOR CELIAC SUFFERERS

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Ursa Major Collaborator
Ursa Major
Posted

That looks interesting. Of course, this far they haven't tried it in REAL stomachs with REAL patients, only in the lab under conditions that sort of mimic the stomach and duodenum. We'll see if it still works when they test it on people. It would be nice to have this enzyme when going out, just in case (but I'd still not purposely eat gluten).

psawyer Proficient
psawyer
Posted

Dr. Kholsa spoke about this project at the Canadian Celiac Association's National Conference last month in Toronto. While promising, it is in the early stages. Clinical trials are expected to start in late 2006 and continue through 2008. Availability of an approved product is another couple of years beyond that, assuming that the stuff actually works in people.

The goal is to deal with small amounts of gluten (less than 500 mg daily), not to allow celiacs to eat gluten at will. It would be enough, though, to pretty much take care of cross-contamination issues.

jerseyangel Proficient
jerseyangel
Posted
Dr. Kholsa spoke about this project at the Canadian Celiac Association's National Conference last month in Toronto. While promising, it is in the early stages. Clinical trials are expected to start in late 2006 and continue through 2008. Availability of an approved product is another couple of years beyond that, assuming that the stuff actually works in people.

The goal is to deal with small amounts of gluten (less than 500 mg daily), not to allow celiacs to eat gluten at will. It would be enough, though, to pretty much take care of cross-contamination issues.

That would be great! Keeping gluten-free is easy--it's that CC that gets me :angry: I hope it sails through the trials, and is deemed effective. Thanks Claire and Peter for this good news :)

Nantzie Collaborator
Nantzie
Posted

I agree.. The only thing that irks me anymore is the cross contamination. So that would be SOOO cool.

Imagine going out to dinner and just being able to pick the croutons off the salad, or just not eat the bread that's on the plate.

Imagine just being able to order the food without watching the server's eyes glaze over when you're trying to explain how important it is that the kitchen staff knows to use a clean pan for your food.

How cool would that be????

Nancy

debmidge Rising Star
debmidge
Posted

the only barrier would be getting this once it's out as a prescription....as sure as shooting the pharamaceutical plans will not want to pay for it....maybe at first when the initial price is so high. We should work from now to clear the pathway with these pharm plans to make sure that they are on board with it from the start. Would the demand that they pay for the prescription come from the individual states' legislatures?

Fiddle-Faddle Community Regular
Fiddle-Faddle
Posted

If it works only in an acid environment like the human stomach, then the hundreds of us who are on acid-blockers either have to go off our acid-blockers or not take this....

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eKatherine Apprentice
eKatherine
Posted
If it works only in an acid environment like the human stomach, then the hundreds of us who are on acid-blockers either have to go off our acid-blockers or not take this....

Your acid mechanism may be whacky, but you must have stomach acid in order to digest your food.

This sounds like the kind of thing that should be sold next to the lact-aid and beano in the supermarket.

mart Contributor
mart
Posted

If it really works and it's really safe to use, I wouldn't care how much I had to pay for it. I agree that eating gluten free was a big deal at first, but not so much now, and that cc is the main issue of concern. To be able to eat out and travel to foreign lands again...gosh, it sounds almost like a dream.

ravenwoodglass Mentor
ravenwoodglass
Posted

The only problem with this is that it does not address the absorption of the gluten by the mucous membranes. By the time the gluten gets too the stomach it's too late anyway. It may show promise as far as relieving the GI components of celiac disease but the toxin would still be entering the bloodstream through the mucous membranes and effecting the brain and other organs.

Guest Viola
Guest Viola
Posted

It's an interesting study, and would certainly be helpful for traveling and staying at relatives houses. That cross contamination gets me every time.

I think acid blockers just block the excess acid, not all of it. I'm on them and still have problems with acid, although it is an improvement. I don't think they would be too much of a problem.

mart Contributor
mart
Posted

I'm curious about this remark the doc made in the article: "and a majority of celiac patients who adopt a restrictive diet still exhibit structural and functional gut abnormalities." Would this explain why many celiacs (such as my son) continue to have stomachaches despite a strict gluten-free diet?

Lister Rising Star
Lister
Posted

i know it wont solve pure gluten problems, but man it is really nice to see a shine of hope for all of us when it comes to cc

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