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Visual Endosopic Dianosis?


jcford33

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jcford33 Rookie

My blood tests point to Celiac, and after my scope, my GI said it sure looked like Celiac. Does Celiac damage have a certain appearance that distinguishes it from Crohn's or other IBS diseases? Thanks!


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happygirl Collaborator

A couple things:

IBS itself does not have any signs that would be visible through an endoscopy/colonoscopy, etc.

IBDs (mainly, Crohns and UC) have distinctive markers. Crohn's damage is predominantly seen in the colon.

Classic celiac damage is seen in the small intestine. "Villous atrophy" or "blunted villi" (the villi are the little hairs in your intestine that are damaged when a Celiac ingests gluten, due to an autoimmune reaction that occurs) are the characteristics of Celiac. The biopsy will confirm it...but if it looked like it, then it probably is (its more common for the doc to "not" see it and the biopsy show Celiac damage, than to "see" it and it come back 'normal')

Since you have positive bloodwork, and an apparently positive biopsy, then you have a gold standard Celiac diagnosis!

plantime Contributor

My endo was a visual one, the doc was looking for ulcers. What he found instead was "spots of redness and inflammation." He wanted to know why the lining was like that, so he took samples from those spots. The lab confirmed my self-diagnosis of celiac disease. While the doc cannot see the villi themselves, there are other factors of celiac disease that can be seen. It is good that he knew what he was seeing when he saw it.

jerseyangel Proficient

Yes, my doctor saw inflammation that he felt was associated with Celiac. He, of course, took biopsies, but advised me to go gluten-free and dairy free that day.

With mine, we were already thinking Celiac.

pinktulip Apprentice
Yes, my doctor saw inflammation that he felt was associated with Celiac. He, of course, took biopsies, but advised me to go gluten-free and dairy free that day.

With mine, we were already thinking Celiac.

My dad's was the same way and his biopsy came back negative the doctor feels he may have gotta a biopsy from a unaffected part.

jerseyangel Proficient
My dad's was the same way and his biopsy came back negative the doctor feels he may have gotta a biopsy from a unaffected part.

Yes, that's a definate possibility, especially if the doctor only took one sample. The damage to the intestine is also patchy, so it can be missed altogether.

pinktulip Apprentice
Yes, that's a definate possibility, especially if the doctor only took one sample. The damage to the intestine is also patchy, so it can be missed altogether.

That's what his doctor is going with and diagnosed him as celiacs. But you can just see the improvment my dad has made. He can actually work all day without worrying about bathroom breaks. sad but true.


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jerseyangel Proficient
That's what his doctor is going with and diagnosed him as celiacs. But you can just see the improvment my dad has made. He can actually work all day without worrying about bathroom breaks. sad but true.

And, you know--that's really the most important thing. Eliminating gluten has caused your dad's health to improve and has let him get on with his life. That's great! :)

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    • par18
      Thanks for the reply. 
    • Scott Adams
      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
    • Scott Adams
      Yes, I meant if you had celiac disease but went gluten-free before screening, your results would end up false-negative. As @trents mentioned, this can also happen when a total IGA test isn't done.
    • Seaperky
      I found at Disney springs and Disney they have specialist that when told about dietary restrictions they come and talk to you ,explain cross contamination measures tsken and work with you on choices. Its the one place I dont worry once I've explained I have celiac disease.  Thier gluten free options are awesome.
    • Churley
      Have you tried Pure Encapsulations supplements? This is a brand my doctor recommends for me. I have no issues with this brand.
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