Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

5htp And Other Natural Antidepressants


rutland

Recommended Posts

rutland Enthusiast

Ive been struggling with anxiety and depression for a few months now. I was determined to find an alternative to the prescription meds. I researched some things in the way of alternative and decided to try 5HTP and SAMe. At first it seemed to be working, I had a couple good days. But as some time went on, about a month and a half, I developed some symptoms that I didnt relate to the supplements. At first I noticed that I was jittery and when I would lay down there was literally noise in my head and a buzzing sensation throughout my body. Then I noticed that my depressive symptoms were coming back full force, and my mind was racing with sad and morbid thoughts. I started waking in the middle of the night, unable to go back to sleep due to a pounding heart and horrible thoughts that I felt I couldnt control. Then I noticed myself becoming paranoid about stuff that would have never bothered me before. Also major brainfog. At first I couldnt figure out why all this was happening because I thought the sups were working at first, but then I had read somewhere that SAMe should not be taken by those with bipolar disorder. I dont have bipolar, but I would think that if it would cause a reaction with someone with bipolar then it may have a reaction with anyone with any kind of chemical imbalance.

I stopped taking these sups and most of the nasty jitteriness and insomnia has gone away, but now Im left with depression and anxiety worse than before. I feel disconnected from myself. I hope I didnt do any damage to my neurological system.

Has anyone ever reacted this way before to supplements? I really didnt want to go the presciption med route but I fear how I can go on with my mind in this state. Is it possible to reverse this kind of thing without meds. Do meds help to balance the chemicals in the brain, and stay that way even if you go off them?


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Ursa Major Collaborator

It is not likely that 5HTP caused those problems. What is in this SAMe? With what you found out about it, it is the likely culprit.

Have you tried St. John's Wort? That combined with 5HTP works for a lot of people. I took 5HTP for a long time (will again, once my naturopathic doctor will let me, he doesn't want me to take too many things right now), and never had any side effects from it. It made me sleep better, and is supposed to be calming.

Fiddle-Faddle Community Regular

I'm sorry you're having such a tough time!

I bet that the last thing you feel like doing is getting up and going outside for some exercise--but it's probably the very best thing for you. If you aren't already doing this, please try to get outside for a good hour of walking (or jogging, if you are up to it), preferably when the sun is out. It really has been proven to make a HUGE difference in people with depression.

Caffeine is another practically universal cause of some of the problems you describe. In spite of the fact that we all drink coffee, tea, or soda, caffeineis a drug, and has a major effect on the mind and the nervous system. So that is something else you might consider changing, if you can (it is very difficult, which shows just how dangerous caffeine can be). I hate to sound preachy about caffeine, as it's an established part of our culture, but it is just as much a drug as nicotine--only socially acceptable. If you are a coffee/cola drinker, perhaps you can try green tea instead, which does have caffeine, but less, and does not have the caustic chemicals found in cola or the acidity of coffee.

Good luck, and I hope things get better by 2007!!! Keep us posted, okay?

plantime Contributor

Sunshine and exercise are good for depression, but if yours is anything like mine, you just don't care enough to get out of bed. You could try St John's Wort, but I recommend going to the doc first to make sure your depression doesn't have a physical cause. Mine is caused by chemical and hormonal imbalances. I refuse to use HRT, so I take Lexapro every day. I don't mind that I need the Lexapro, it is no different than someone needing insulin or thyroid meds. Depression as a disease has a great deal of social stigma attached to it, but it really is a treatable disease. Talk to your doc before you try anything else, at the very least, get a physical w/labwork.

Nancym Enthusiast

Caffeine can be a good anti-depressant but if you have too much it can create anxiety.

But yeah it sounds like you did a good thing getting off the 5htp and SAMe. On the pharma meds they'd wean you off, not stop abruptly though. I know that there are at least 2 types of chemical issues that cause depression so it might just be possible you're on the wrong supplement for them. The pharma solution has a few different choices, but I don't know about supplements. This might be something you should see a doctor about, especially if you're very concerned.

Fiddle-Faddle Community Regular

Depression is definitely a chemical situation! But the sunshine and exercise help you make those chemicals so that you either need less of the pharma verisons or (hopefully) none at all. If you can get out of bed to get to the doctor, you can get out of bed to walk around the block. It's the getting out of thehouse that is the hardest part.

When I had post-partum depression (yes, that one is chemical, too), it took the combined threats from the OBGYN (to put me on antidepression meds which would force me to terminate breastfeeding) and a friend with a slightly older baby (so she'd been through it) to come DRAG me outside before I finally got out of the house.

Good luck. Christmas is a very stressful time when you are depressed. You know we all care here, if that helps, any. Sometimes we just need someone to take care of us a little, too. I don't know how that is chemical, but someday, some scientist will probably come up with a reason that it is, too, like tucking you in raises seratonin levels or something! :lol:

Would chocolate help?

plantime Contributor

That's the problem with some forms of depression: not everyone has someone that will drag them out for exercise outdoors. The weather is not always cooperative, either: it's hard to walk in sunshine when you have a week straight of rain and clouds. Sunshine and exercise also does not cure all forms of depression (they do nothing for my hormone imbalance), that is why it is important to see your doctor for an exam.


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Fiddle-Faddle Community Regular

Wish I could remember where I read this, but I did read that it doesn't matter if it's sunny or rainy as long as you are outdoors during daylight hours. It makes sense, because you CAN be sunburned on a totally grey, cloudy day. The same holds true for adjusting to a new time zone, by the way--spend as much time as possible outdoors during daylight hours.

There ARE good doctors out there; as long as you can find one that doesn't just write a scrip for drugs without trying non-drug alternatives first, the best plan is to see one. But there are so many lousy doctors out there who try to put people on antidepressants when they really don't need them.

I know people who have been helped through major depressions by antidepressants. I also know people who have had years of their lives ruined by antidepressants. I shudder to think what it would have done to me and my baby to have taken antidepressants back then when I didn't need them. On the other hand, if they help you, go for it! Just make sure you can stop taking them if they make you worse.

rutland Enthusiast

Thanks for your advice and support.

Fiddle faddle, I do get outdoors, I try to everyday. I dont drink a lick of caffine, so I know thats not it. I believe I have a temporary chemical imbalance due to poor digestion. The good news is I think that since Ive been using digestive enzymes my mood and mind seems to be lifting a little. Even today I notice a great improvement from just a few days ago, so I may not be needing those antidepressants after all :rolleyes:

Im going to keep investigating ways to bolster my nutrition, because I believe that nutrition is the key to all my woes right now. I say this because there are days when Im digesting my food better and eating better and those are the days when my anxiety and depression are most lifted. I swear, we all are our best physicians. Although I will be seeing a doctor.

plantime Contributor

I'm glad that you are having good days! Perhaps you have become anemic with the poor digestion. Hopefully the digestive aids will continue to help you, and you will start to feel even better!

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - xxnonamexx posted a topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      0

      Fermented foods, Kefir, Kombucha?

    2. - SamAlvi replied to SamAlvi's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      7

      High TTG-IgG and Normal TTG-IgA

    3. - knitty kitty replied to lizzie42's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      6

      Son's legs shaking

    4. - lizzie42 replied to lizzie42's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      6

      Son's legs shaking

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      132,877
    • Most Online (within 30 mins)
      7,748

    Ruth Margaret
    Newest Member
    Ruth Margaret
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Upcoming Events

  • Posts

    • xxnonamexx
      I have read fermented foods like sauerkraut, pickles, Kefir, Kombucha are great for gut health besides probiotics. However I have searched and read about ones that were tested (Kefir, Kombucha) and there is no clear one that is very helpful. Has anyone take Kefir, Kombucha and noticed a difference in gut health? I read one is lactose free but when tested was high in lactose so I would probably try a non dairy one. Thanks
    • SamAlvi
      Thanks again for the detailed explanation. Just to clarify, I actually did have my initial tests done while I was still consuming gluten. I stopped eating gluten only after those tests were completed, and it has now been about 70 days since I went gluten-free. I understand the limitations around diagnosing NCGS and the importance of antibody testing and biopsy for celiac disease. Unfortunately, where I live, access to comprehensive testing (including total IgA and endoscopy with biopsy) is limited, which makes things more complicated. Your explanation about small-bowel damage, nutrient absorption, and iron-deficiency anemia still aligns closely with my history, and it’s been very helpful in understanding what may be going on. I don't wanna get Endoscopy and I can't start eating Gluten again because it's hurt really with severe diarrhea.  I appreciate you taking the time to share such detailed and informative guidance. Thank you so much for this detailed and thoughtful response. I really appreciate you pointing out the relationship between anemia and antibody patterns, and how the high DGP IgG still supports celiac disease in my case. A gluten challenge isn’t something I feel safe attempting due to how severe my reactions were, so your suggestion about genetic testing makes a lot of sense. I’ll look into whether HLA testing is available where I live and discuss it with my doctor. I also appreciate you mentioning gastrointestinal beriberi and thiamine deficiency. This isn’t something any of my doctors have discussed with me, and given my symptoms and nutritional history, it’s definitely worth raising with them. I’ll also ask about correcting deficiencies more comprehensively, including B vitamins alongside iron. Thanks again for sharing your knowledge and taking the time to help. I’ll update the forum as I make progress.
    • knitty kitty
      Blood tests for thiamine are unreliable.  The nutrients from your food get absorbed into the bloodstream and travel around the body.  So, a steak dinner can falsely raise thiamine blood levels in the following days.  Besides, thiamine is utilized inside cells where stores of thiamine are impossible to measure. A better test to ask for is the Erythrocyte Transketolace Activity test.  But even that test has been questioned as to accuracy.  It is expensive and takes time to do.   Because of the discrepancies with thiamine tests and urgency with correcting thiamine deficiency, the World Health Organization recommends giving thiamine for several weeks and looking for health improvement.  Thiamine is water soluble, safe and nontoxic even in high doses.   Many doctors are not given sufficient education in nutrition and deficiency symptoms, and may not be familiar with how often they occur in Celiac disease.  B12 and Vitamin D can be stored for as long as a year in the liver, so not having deficiencies in these two vitamins is not a good indicator of the status of the other seven water soluble B vitamins.  It is possible to have deficiency symptoms BEFORE there's changes in the blood levels.   Ask your doctor about Benfotiamine, a form of thiamine that is better absorbed than Thiamine Mononitrate.  Thiamine Mononitrate is used in many vitamins because it is shelf-stable, a form of thiamine that won't break down sitting around on a store shelf.  This form is difficult for the body to turn into a usable form.  Only thirty percent is absorbed in the intestine, and less is actually used.   Thiamine interacts with all of the other B vitamins, so they should all be supplemented together.  Magnesium is needed to make life sustaining enzymes with thiamine, so a magnesium supplement should be added if magnesium levels are low.   Thiamine is water soluble, safe and nontoxic even in high doses.  There's no harm in trying.
    • lizzie42
      Neither of them were anemic 6 months after the Celiac diagnosis. His other vitamin levels (d, B12) were never low. My daughters levels were normal after the first 6 months. Is the thiamine test just called thiamine? 
    • knitty kitty
      Yes, I do think they need a Thiamine supplement at least. Especially since they eat red meat only occasionally. Most fruits and vegetables are not good sources of Thiamine.  Legumes (beans) do contain thiamine.  Fruits and veggies do have some of the other B vitamins, but thiamine B 1 and  Cobalamine B12 are mostly found in meats.  Meat, especially organ meats like liver, are the best sources of Thiamine, B12, and the six other B vitamins and important minerals like iron.   Thiamine has antibacterial and antiviral properties.  Thiamine is important to our immune systems.  We need more thiamine when we're physically ill or injured, when we're under stress emotionally, and when we exercise, especially outside in hot weather.  We need thiamine and other B vitamins like Niacin B 3 to keep our gastrointestinal tract healthy.  We can't store thiamine for very long.  We can get low in thiamine within three days.  Symptoms can appear suddenly when a high carbohydrate diet is consumed.  (Rice and beans are high in carbohydrates.)  A twenty percent increase in dietary thiamine causes an eighty percent increase in brain function, so symptoms can wax and wane depending on what one eats.  The earliest symptoms like fatigue and anxiety are easily contributed to other things or life events and dismissed.   Correcting nutritional deficiencies needs to be done quickly, especially in children, so their growth isn't stunted.  Nutritional deficiencies can affect intelligence.  Vitamin D deficiency can cause short stature and poor bone formation.   Is your son taking anything for the anemia?  Is the anemia caused by B12 or iron deficiency?  
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.