Reviewing My 'negative' Test Results

[dbmamaz]

I looked at the test results the first time (I insisted on a copy) and was suprised that, yes, they were all negative. However, I remembered seeing a post once that said if you were too low on something, that meant the test was not valid. Well, now I want to take a closer look. I know lots of ppl have posted this kind of thing and gotten very little response . .. but if you cant help with the specifics, I'd love a link to a good overview of what the tests mean.

Here's my results (keep in mind, I'd been off gluten 2 mo already):

Antigliadin Abs, IgA: 0 (neg 0-4)

Antigliadin Abs, IgG: 0 (neg 0-9)

t-Transglutaminase (tTG) IgA 1 (Neg 0-3)

t-Transglutaminase (tTg) IgG 1 (Neg 0-5)

Immunoglobulin A, Qn, Serum 325 (70-400)

So, that last one . .. its pretty high considering i'd been off gluten for 2 months, maybe? I dont know what it means . .. anyone?

[Lisa]

I looked at the test results the first time (I insisted on a copy) and was suprised that, yes, they were all negative. However, I remembered seeing a post once that said if you were too low on something, that meant the test was not valid. Well, now I want to take a closer look. I know lots of ppl have posted this kind of thing and gotten very little response . .. but if you cant help with the specifics, I'd love a link to a good overview of what the tests mean.

Here's my results (keep in mind, I'd been off gluten 2 mo already):

Antigliadin Abs, IgA: 0 (neg 0-4)

Antigliadin Abs, IgG: 0 (neg 0-9)

t-Transglutaminase (tTG) IgA 1 (Neg 0-3)

t-Transglutaminase (tTg) IgG 1 (Neg 0-5)

Immunoglobulin A, Qn, Serum 325 (70-400)

So, that last one . .. its pretty high considering i'd been off gluten for 2 months, maybe? I dont know what it means . .. anyone?

Here is a link that you may be interested in:

Open Original Shared Link

I am not so good with interpreting testing, but I do know that being gluten free for two months would certainly effect your testing.

[Fiddle-Faddle]

Those tests measure your production of antibodies against gluten. If you weren't eating gluten for two months, then you wouldn't be producing those antibodies, even with celiac. That's why it is so important to be eating gluten when you have the bloodwork done.

[happygirl]

The test you are thinking about is the total IgA (or the last test on your list), but that test isn't "for" Celiac. It merely tests to see if you are IgA deficient. If you are IgA deficient, then you can't produce enough IgA antibodies, which makes the other tests (particularly the AGA IgA, the tTG IgA, and the EMA IgA) tests unreliable - if you are IgA deficient.

I am not a doctor, but based on your test results, it doesn't look like you are IgA deficient. Check out the link MG gave you-it helps explain better.

If you have Celiac, the fact that you were gluten-free for 2 months negates the purpose of the testing.

[jayhawkmom]

Antigliadin Abs, IgA: 0 (neg 0-4)

Antigliadin Abs, IgG: 0 (neg 0-9)

t-Transglutaminase (tTG) IgA 1 (Neg 0-3)

t-Transglutaminase (tTg) IgG 1 (Neg 0-5)

Immunoglobulin A, Qn, Serum 325 (70-400)

So, that last one . .. its pretty high considering i'd been off gluten for 2 months, maybe? I dont know what it means . .. anyone?

The IgA Serum is not a test for Celiac, it simply tests your IgA level, which if negative would negate the testing. However, yours in well within the normal range. If it were under 70 it would be indicative of IgA deficiency. However, your results are totally normal.

The other results look like absolute negatives to ME. But, if you'd been gluten free for a while, there really was no point in having blood tests done. They are not accurate unless you are consuming gluten. (Or to test for diet compliance after going gluten-free, in which case Zero's are what you want!)

[dbmamaz]

Thanks for all the replies. I really appreciate it

Part of why I keep wondering is that I still really think I have some other relatives with the same problems and I guess if it WAS celiac, that might give them some motivation to work on their issues from a diet perspective. One of my sons was tested recently (mental health issues, frequent D and C all his life, nausea every morning - but i think more from meds), and I still am worrying about the youngest (dropping thru the growth charts, actually prefers sandwhiches on rice cakes, a mysterious blister on his nose for a week). My biggest worry is my sister (chronic fatigue, fibromyalgia, mysterious neurological disorders, and serious mental health issues). Oh, and dont forget the hubby (frequent stomach distress and huge bloated belly by the end of every day)

For me, theres I doubt I'll eating gluten again . .. my improvements were too dramatic. However, if its just an allergy, i'll test it again .. if its celiac then I shouldnt . .. maybe i'lll take the genetic test some day, we'll see.

thanks again