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What Does Having Hl-dq2 + Subset Of That Gene Mean?

Newbyliz

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Newbyliz Rookie
Newbyliz
Posted

I am currently scheduled for my second upper endoscopy in a week bcause my gastro. said that I tested positive for HLA-DQ2 plus a subset of that gene and he feels that, that alone puts me in a moderate risk group for developing celiac since my symptoms are pretty bad. I get confused about the genetic testing because I know it doesn't mean you will get celiac it just means you have the genetic predisposition needed to develop it. Does having the HLA-DQ2 plus a subset of it really put me at a higher risk? I do have to say that I have been trying to eat gluten containing foods at each meal for the past week and I am not feeling too well. My stools are really loose and I am really foggy, it seems so strange to be conciously eating something that potentially is harmful to you but I know its necessary for the testing. I am a little skeptical going through another upper endoscopy since the first didn't show anything but I guess I just have to trust my new doc and pray that he sees something that will explain how rotten I feel. I am so tired I want to know why I am deficient in vitamin b12 and d and I want to get to a point where this isn't something that haunts me each day. Even if the endoscopy comes back like the first and just shows inflammation throughout my whole digestive tract I am definitely going to try a gluten free diet. Sorry to be rambling and fussing I just am so thankful that this forum is here and that there are people who understand completely what you are going through in trying to, for once an for all, figure out what is wrong.

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homemaker Enthusiast
homemaker
Posted
I am currently scheduled for my second upper endoscopy in a week bcause my gastro. said that I tested positive for HLA-DQ2 plus a subset of that gene and he feels that, that alone puts me in a moderate risk group for developing celiac since my symptoms are pretty bad. I get confused about the genetic testing because I know it doesn't mean you will get celiac it just means you have the genetic predisposition needed to develop it. Does having the HLA-DQ2 plus a subset of it really put me at a higher risk? I do have to say that I have been trying to eat gluten containing foods at each meal for the past week and I am not feeling too well. My stools are really loose and I am really foggy, it seems so strange to be conciously eating something that potentially is harmful to you but I know its necessary for the testing. I am a little skeptical going through another upper endoscopy since the first didn't show anything but I guess I just have to trust my new doc and pray that he sees something that will explain how rotten I feel. I am so tired I want to know why I am deficient in vitamin b12 and d and I want to get to a point where this isn't something that haunts me each day. Even if the endoscopy comes back like the first and just shows inflammation throughout my whole digestive tract I am definitely going to try a gluten free diet. Sorry to be rambling and fussing I just am so thankful that this forum is here and that there are people who understand completely what you are going through in trying to, for once an for all, figure out what is wrong.

I would like that answer too! I also have HLA-DQ2 plus what I think is a subset of that ...I am so confused

Newbyliz Rookie
Newbyliz
Posted
  • Author

I see that you went gluten free the beginning of October. Do you feel any better? Thank you so much for your reply.

homemaker Enthusiast
homemaker
Posted
I see that you went gluten free the beginning of October. Do you feel any better? Thank you so much for your reply.

I now have been gluten free for 2 months now...and yes I feel so much better....an almost total turnaround intestinally....

Newbyliz Rookie
Newbyliz
Posted
  • Author

I can't wait to get the second endoscopy over so that I can see if I feel better on the gluten free diet. Did you say or not if you had a positive biopsy or bloodwork? Thanks!

homemaker Enthusiast
homemaker
Posted
I can't wait to get the second endoscopy over so that I can see if I feel better on the gluten free diet. Did you say or not if you had a positive biopsy or bloodwork? Thanks!

My bloodwork was negative and I did not have an endoscope down...my Doc I went to for the blood test basically told me to go out an celebrate with a bagel...after my blood test came back negative...

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    • trents
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      By trents · Posted

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    • Dizzyma
      Newly diagnosed mam to coeliac 11 year old

      By Dizzyma · Posted

      Hi all, I have so many questions and feel like google is giving me very different information. Hoping I may get some more definite answers here. ok, my daughter has been diagnosed as a coeliac as her bloods show anti TTG antibodies are over 128. We have started her  on a full gluten free diet. my concerns are that she wasn’t actually physically sick on her regular diet, she had tummy issues and skin sores. My fear is that she will build up a complete intolerance to gluten and become physically sick if she has gluten. Is there anything to be said for keeping a small bit of gluten in the diet to stop her from developing a total intolerance?  also, she would be an anxious type of person, is it possible that stress is the reason she has become coeliac? I read that diagnosis later in childhood could be following a sickness or stress. How can she have been fine for the first 10 years and then become coeliac? sorry, I’m just very confused and really want to do right by her. I know a coeliac and she has a terrible time after she gets gluttened so just want to make sure going down a total gluten free road is the right choice. thank you for any help or advise xx 
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