Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Oral And Rectal Challenge Testing Of The Mucosa


ravenwoodglass

Recommended Posts

ravenwoodglass Mentor

There has been some recent debate on whether gluten is absorbed into the system through any mucosa other than the intestines. In the US mucosal testing is unheard of they would rather make us sick for weeks or months to do an expensive and inherently risky endo and biopsy. Other countrys have found that that torture may not be needed and that by using a gluten laden patch or infusion or suppository that the histological changes can be detected in the mucous membranes within a relatively short time. There are many more articles out there a search of rectal or mucosal challenge and celiac will bring them up.

Here is one study on the use of detecting celiac through rectal mucosa challenge off of Pub Med

Open Original Shared Link

And another

Open Original Shared Link

And one last one on nasal mucosa testing

Open Original Shared Link


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Nancym Enthusiast

None of those links worked for me!

psawyer Proficient

Those links appeat to have been pasted in from another thread:

Open Original Shared Link

They work there, but long urls are displayed with an elipsis replacing a number of characters in the middle. If the displayed version is pasted, it does not work.

ravenwoodglass Mentor
Those links appeat to have been pasted in from another thread:

Open Original Shared Link

They work there, but long urls are displayed with an elipsis replacing a number of characters in the middle. If the displayed version is pasted, it does not work.

They were pasted and I did not realize they would not open after pasting. I'll see if I can correct that. Thanks for posting the link to the other post.

One real good reason for us to get this info out is it would be nice if US doctors knew about some of the less invasive forms of testing and hopefully if people ask their GI doctors about it and show them some of the studies on the validity of mucosal testing we can get it used in the US and more people will be able to be diagnosed without having to be made ill to do so.

Edit I think I was able to fix the problem. Thanks guys seems the world forces me to be more computer literate every day, whether I want to or not.

  • 4 years later...
domesticactivist Collaborator

I just had someone tell me about Cyrex labs cross-reactivity tests and when I went to their site saw that they offer Mucosal Gluten Reactivity Screen that I'd seen mentioned here on this site a couple times. I'm very interested to learn more about this.

Open Original Shared Link

Does anyone have neutral information on the validity of the Cyrex labs tests?

Skylark Collaborator

Does anyone have neutral information on the validity of the Cyrex labs tests?

That's just salivary IgA. It's no better validated than fecal.

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      129,653
    • Most Online (within 30 mins)
      7,748

    RochelleL
    Newest Member
    RochelleL
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.2k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • SophiesMom
      I have been looking for new dishes. I was surprised to find dishes made of wheat straw. Are these safe for us? I'm very careful to avoid products that may contain gluten. I never thought I might have to check for wheat in dishes.
    • trents
      Welcome to the forum, @Hope07! The reference range would refer to what is considered normal in healthy people. So, 7 or less would mean there is no indication of "active" celiac disease. Apparently, you are doing very will in avoiding gluten. The "Tissue Transglutaminase IGA" is the centerpiece antibody test that clinicians run when checking for celiac disease. My only reservation would be that whenever the TTG-IGA test is run, a "total IGA" test should also be run to check for IGA deficiency. When IGA deficiency is present, other IGA tests, such as the TTG-IGA can be artificially low and result in false positives. In the absence of any symptoms indicating your celiac disease is not under control, however, I would take the result you posted at face value.
    • StevieP.
      Going on a cruise next week and I’m a celiac. Bought a bottle of GliandinX. Should I just take two tablets per day as a precaution? Never tried this before!! Any help is appreciated!!
    • Hope07
      Hola! Not sure if I’m asking this in the right place so apologies if not! I just had a full blood count as part of my first check up after being diagnosed with celiac disease 7 years ago!! With Covid lockdowns then living in Spain for 3 years and now back in the UK, I kept getting missed in the system but finally I’ve had a check up! Does anyone know what this means?  Tissu transglutaminase IgA lev:  0.30 U/ml Reference range:  Below 7 Thank you!   
    • DebD5
      Thank you so very much. 
×
×
  • Create New...