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Oral And Rectal Challenge Testing Of The Mucosa


ravenwoodglass

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ravenwoodglass Mentor

There has been some recent debate on whether gluten is absorbed into the system through any mucosa other than the intestines. In the US mucosal testing is unheard of they would rather make us sick for weeks or months to do an expensive and inherently risky endo and biopsy. Other countrys have found that that torture may not be needed and that by using a gluten laden patch or infusion or suppository that the histological changes can be detected in the mucous membranes within a relatively short time. There are many more articles out there a search of rectal or mucosal challenge and celiac will bring them up.

Here is one study on the use of detecting celiac through rectal mucosa challenge off of Pub Med

Open Original Shared Link

And another

Open Original Shared Link

And one last one on nasal mucosa testing

Open Original Shared Link


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Nancym Enthusiast

None of those links worked for me!

psawyer Proficient

Those links appeat to have been pasted in from another thread:

Open Original Shared Link

They work there, but long urls are displayed with an elipsis replacing a number of characters in the middle. If the displayed version is pasted, it does not work.

ravenwoodglass Mentor
Those links appeat to have been pasted in from another thread:

Open Original Shared Link

They work there, but long urls are displayed with an elipsis replacing a number of characters in the middle. If the displayed version is pasted, it does not work.

They were pasted and I did not realize they would not open after pasting. I'll see if I can correct that. Thanks for posting the link to the other post.

One real good reason for us to get this info out is it would be nice if US doctors knew about some of the less invasive forms of testing and hopefully if people ask their GI doctors about it and show them some of the studies on the validity of mucosal testing we can get it used in the US and more people will be able to be diagnosed without having to be made ill to do so.

Edit I think I was able to fix the problem. Thanks guys seems the world forces me to be more computer literate every day, whether I want to or not.

  • 4 years later...
domesticactivist Collaborator

I just had someone tell me about Cyrex labs cross-reactivity tests and when I went to their site saw that they offer Mucosal Gluten Reactivity Screen that I'd seen mentioned here on this site a couple times. I'm very interested to learn more about this.

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Does anyone have neutral information on the validity of the Cyrex labs tests?

Skylark Collaborator

Does anyone have neutral information on the validity of the Cyrex labs tests?

That's just salivary IgA. It's no better validated than fecal.

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