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- Wamedh Taj-Aldeen posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms0Positive TTG antibody and negative EMA antibody
I recently reviewed a patient with a positive tissue transglutaminase (tTG) antibody but negative endomysial antibodies (EMA). The patient is asymptomatic, and duodenal biopsies—taken while on a normal gluten-containing diet—were reported as normal. Given the discordant serology and absence of histological changes, I understand that the probability of ... -
- Cat M posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms0Weakly positive DGP IgA
TTG IgA <2 Ttg IgG 3 DGP IgG 4 Total IgA was not performed. My GP thinks I am gluten sensitive and do not have celiac. I would like to consume gluten for a few weeks and retest, or consult a gastroenterologist now. I am symptomatic, which is why we tested. I do have the HLA DQ2. Is it possible this is a false positive? What would cause... -
- trents replied to LynnM's topic in Gluten-Free Foods, Products, Shopping & Medications6Is "Shield" skincare products gluten-free?
@LynnM, when you say, "today, his numbers were high", what numbers do you refer to? Are you speaking of celiac antibody scores? Can you be more specific and can you post the test names, the numbers and the reference ranges for the tests? So, I am understanding you to say that topical exposure to gluten doesn't cause him GI reactions but ingestion of... -
- Ginger38 posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms0Abnormal Labs, Should I Be Concerned?
So I recently had blood work and my hemoglobin, hematocrit, protein and alkaline phosphatase were all low. They have never been low in the past but since august of last year I have been on the in and off gluten rollercoaster as I mentioned in previous posts. Should I be concerned with these new findings? I am worried I have made myself really sick and done... -
- LynnM replied to LynnM's topic in Gluten-Free Foods, Products, Shopping & Medications6Is "Shield" skincare products gluten-free?
Thank you Scott. My son doesn't have a reaction topically, only when ingested. Interestingly though, the doc told us the face cream getting gluten into his bloodstream doesn't do the damage akin to when gluten is ingested. He had no reaction when using the face cream, it only presented in blood-work. I'm hopeful from all the comments today and will wait for...
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By Wamedh Taj-Aldeen · Posted
I recently reviewed a patient with a positive tissue transglutaminase (tTG) antibody but negative endomysial antibodies (EMA). The patient is asymptomatic, and duodenal biopsies—taken while on a normal gluten-containing diet—were reported as normal. Given the discordant serology and absence of histological changes, I understand that the probability of coeliac disease is low. However, I would appreciate your guidance on the following: Is routine follow-up required in such a case? What is the risk of progression to overt coeliac disease in the future? Would HLA DQ2/DQ8 typing be useful here to help guide long-term management or exclude the diagnosis confidently? I would be grateful for your thoughts. -
TTG IgA <2 Ttg IgG 3 DGP IgG 4 Total IgA was not performed. My GP thinks I am gluten sensitive and do not have celiac. I would like to consume gluten for a few weeks and retest, or consult a gastroenterologist now. I am symptomatic, which is why we tested. I do have the HLA DQ2. Is it possible this is a false positive? What would cause that?
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@LynnM, when you say, "today, his numbers were high", what numbers do you refer to? Are you speaking of celiac antibody scores? Can you be more specific and can you post the test names, the numbers and the reference ranges for the tests? So, I am understanding you to say that topical exposure to gluten doesn't cause him GI reactions but ingestion of gluten does but at the same time you are attributing the "high numbers" to the topical exposure?
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So I recently had blood work and my hemoglobin, hematocrit, protein and alkaline phosphatase were all low. They have never been low in the past but since august of last year I have been on the in and off gluten rollercoaster as I mentioned in previous posts. Should I be concerned with these new findings? I am worried I have made myself really sick and done damage or something this past year
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Thank you Scott. My son doesn't have a reaction topically, only when ingested. Interestingly though, the doc told us the face cream getting gluten into his bloodstream doesn't do the damage akin to when gluten is ingested. He had no reaction when using the face cream, it only presented in blood-work. I'm hopeful from all the comments today and will wait for the GI doc to reply. If he is cleared to use it, I will encourage SHIELD to get a gluten-free certification
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