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Seasonal Allergies Triggering Celiac


JoD

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JoD Newbie

I've been gluten free for 9 months and this year allergies are at a high. I was going well and feeling better until my allergies really have bothered me. I now have the worst IBS and haven't taken anything with gluten.

Does anyone know if regular allergies can trigger your celiac? Help! It's horrible and I'm sick of being in the house due to not wanting to go to far.


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trents Grand Master

Do you live in a farming area where wheat, barley or rye is being grown? Grains seeded in the autumn (i.e. "winter wheat") may be pollinating by now. Don't know if that would be a possible connection but the thought crossed my mind.

Mother of Jibril Enthusiast

I've been having mild abdominal pain for more than a year. The gluten-free diet helped a LOT (I started about the same time as you), but... the pain is back. Not as bad as before, and I'm positive that I'm not being glutened. In February I started having anaphylactic reactions and I've learned a lot of interesting things about allergies. For example, did you know that your abdomen is full of mast cells? They play an important role in menstruation, orgasm, defecation, etc... but things can get out of control. Some new research is showing that abnormal mast cell activity (too many mast cells and/or mast cells that release their contents too easily) is involved in:

- prostatitis (Open Original Shared Link)

- interstitial cystitis (Open Original Shared Link)

- endometriosis (Open Original Shared Link)

- and possibly IBS (Open Original Shared Link)

My allergist recommended that I take 10mg of Zyrtec (cetirizine) per day and 20mg of Pepcid (famotidine) twice a day. The interesting thing about Pepcid and related medicines like Zantac is that they reduce acid in your stomach by blocking histamine production. I can tell when my morning dose is wearing off because that cramping feeling comes back in my lower abdomen :( The last two nights I've taken a dose of Tylenol to get rid of it. Monday I have an appointment with a gastroenterologist... I'll be very curious to hear what he thinks about all of this.

JoD Newbie

[Let me know! It's very frustrating!

Mother of Jibril Enthusiast

The appointment today was good!

I've had a LOT of testing... celiac panels, urinalysis, stool analysis, chest x-ray... today the doctor suggested we do an endoscopy to look for mastocytosis (too many mast cells in my GI system). I know how frustrating it is when you're in pain and you just keep going from doctor to doctor looking for answers, but hang in there and keep insisting that you need to figure out what's going on! It's definitely possible to get abdominal symptoms from allergies.

BTW... have you ever tried eliminating other foods? I found it helpful to take corn out of my diet. Other common culprits include soy, dairy, eggs, and nightshades.

mindwiped Rookie

It could be just the allergies, and nothing celiac related at all. I have year round allergies, but when ragweed goes into high gear, I have so much post nasal drip, that I start having stomach issues, since I can't blow my nose enough to keep it from going down my throat. Non-sedating antihistamines (Zyrtec or Clariten) could help, just be sure to check the gluten status on any off-brands.

Mrs. Smith Explorer

I was just looking this subject up! Im having a bad seasonal allergy attack for the last few days and now today I am nauseas! It must just be the allergies. Im on my period too so Im sure thats not helping!! <_<


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    • trents
      Welcome to celiac.com, @Wamedh Taj-Aldeen! Just curious, what is your relationship to the patient? Are you the attending physician? A medical student? A consulted physician? Was a total IGA test ordered? Some physicians are under the dated and mistaken impression that such is only necessary in young children. If total IGA is low, other IGA antibody numbers will be artificially depressed. By the way, it is not unusual to have a positive TTG-IGA and a negative EMA. Are the TTG-IGA numbers borderline high or unequivocally high? There are other diseases, medical conditions, medications and even foods (cow's milk protein) that can cause elevated TTG-IGA numbers besides celiac disease but when this is the case, the numbers are usually not dramatically elevated. It can also be the case that villous damage was patchy and affected areas were missed during the biopsy. Or, onset of celiac disease was very recent and villous atrophy has not yet progressed to the point of detectability.  We also have occasional anecdotal reports in this online community of positive antibody testing with negative histology, as you report. But we also know that gluten intolerance can manifest itself apart from enteropathy. It can damage other organ systems. Many celiacs are of the "silent" type, meaning there is an absence or a relative absence of symptoms until the disease has become advanced and there is significant damage to the villous lining or other organ systems. But to answer your questions: 1. I would definitely pursue a routine follow-up and recheck of the antibodies. And, I would order a complete celiac panel including total IGA and IGG stuff in say, six months. Sooner if symptoms manifest. 2. It is impossible to say what is the risk of the future development of over celiac disease. I refer you back to my #1 above concerning rechecking.  3. I would definitely pursue HLA DQ2/DQ8 typing as it can be used as a rule out for celiac disease, though not quite with 100% dependability. I hope my thoughts prove helpful to you.
    • trents
      Welcome to the forum, @dominiqueccms! Unfortunately, your story is all too common. Some older physicians are dismissive when it comes to gluten intolerance disorders and have this attitude like, "It's the latest fad disease." My advice to you is to get another doctor who has more current knowledge in this area and will take this seriously. In the meantime, this might be helpful: In six months to a year you would do well to get your antibody numbers rechecked to see if you are succeeding in your efforts to eat gluten free. Do you have the numbers from the original testing?
    • trents
      By the way, you need to repost those numbers in your first post and add the reference ranges. Different labs use different reference ranges so the test scores by themselves aren't very helpful, especially when the values may be borderline positive. It would need to be in a new post window as the edit function times out quickly such that you can't go back and make changes to the original. What symptoms do you have? What has led you to investigate the possibility of having celiac disease?
    • Cat M
      I ate two pieces of toast each morning for three weeks prior to testing. The rest of the day I ate whatever. I am going to increase the gluten for four weeks and ask my doc to retest. I did read that false positives are possible, so I think it’s reasonable to retest. But I am very new to this, so not feeling confident.
    • trents
      Welcome to celiac.com, @Cat M! Were you consuming generous amounts of gluten for a significant period of time (weeks/months) before the blood draw and test results you posted? I ask because you say you would like to be retested after consuming gluten for a few weeks. Current guidelines for the gluten challenge call for the daily consumption of at least 10g of gluten (the amount found in about 4-6 slices of wheat bread) for at least 2 weeks. But I would go for longer than that to be sure, say 4 weeks. Testing is invalid when people have been gluten free or even skimping on it.
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