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Help Understanding Test Results


Sarabethy

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Sarabethy Newbie

I'm a newbie here and recently have undergone some testing for Celiac Disease. If anyone could help me understand some of these test results, I would greatly appreciate it. A little background information, I have been off of gluten completely for 4 years and have been tested positive for a gluten allergy. I have some other health issues and my doctor recently ran the Celiac disease HLA DQ test (results of which I need help interpreting). It appears negative, but I have a few alleles (I think?) and they ran a celiac panel. Celiac panel was normal, but since I have been off gluten for 4 years now, according to my understanding that test isn't completely accurate if you aren't actively eating gluten.

Celiac Disease HLA DQ:

DQ2 (DQA1 0501/0505, DQB1 02XX) Negative

DQ8 (DQA1 03XX, DQB1 0302) Negative

Final Results:

DQA1*01:MV, 05:EF

DQB1*03: JVYH, 05:01

Code Translation:

JVYH 01/27/28/29/35

MV 01/04/05

EF 05/09

The Patient is positive for DQA1*05, one half of the DQ2 heterodimer. The Celiac Disease risk from the HLA DQA/DQB genotype is approximately 1:1842 (0.05%)....etc.

So what I see is that I am negative for this, but what do these alleles mean? Do they mean anything to me?


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