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If Celiac Is Caught And Treated Early Is There Still Risk For Other Autoimmune?


guest134

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guest134 Apprentice

As some of you know I may be diagnosed with early celiac. If my ab's don't go down and it is proven celiac and we treat it am I still at risk for developing other autoimmune diseases? We already checked 15 different antibodies, negative for everything so as of right now it is just the possibility of early celiac. Thoughts?


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shadowicewolf Proficient

It is always possible to develop one. I think the fact that ya have one already puts ya at a slightly higher risk, but treating it early enough probably stopped it from getting any higher.

GottaSki Mentor

That is a very good question. I doubt anyone can give you odds on this one. All autoimmune disorders are top on my list for much more research needed.

What I can tell you is if your next round of antibody tests does not have lower numbers -- I would advise you (as I would my own children) -- to remove ALL gluten for at least three months - six is better - then test blood again to see if antibodies are reduced.

AI symptoms can occur with celiac disease - without "classic" symptoms.

You have done a great deal of research - I believe you will find a good path that will lead to health and limit the risks that gluten may cause you.

nvsmom Community Regular

From what I've read, yes, once your body has started making antibodies against itself you are more likely to develop another autoimmune disease than someone who does not have AI diseases. Some medical circles are even starting to classify the diseases into groups: celiac disease falls into the Type III Polyglandular Autoimmune Syndrome. Heres's a quick overview:

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It makes sense to me when I consider my own personal experiences because my immune system has attacked my intestine, thyroid and platelets, and I suspect it is attacking my soft connective tissues too.

Celiac disease is not the main link in this syndrome, it's thyroiditis that is the common disease. I do wonder if my celiac had been discovered earlier if I would have devloped my problems but after reading about all the diseases and how they often overlap, I kind of doubt it was the cause... although it might have helped it to appear earlier in my life that it might have otherwise.

This is just my opinion and interpretation of what I've read though. I could be way off.

ButterflyChaser Enthusiast

I was talking to a prof of Weil Cornell the other night, and she confirmed that a) we don't know much about these disorders, especially because they involve multiple organs, and B) it is more correct to talk of "a condition of autoimmunity" rather than of singular diseases, ie a body's tendency to attack its own tissues.

That said, you may create antibodies and never develop the disease: my endo has arthritis rheumatoid, and has had antithyroid antibodies for twenty years, but she never developed thyroid disease.

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    • par18
      Thanks for the reply. 
    • Scott Adams
      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
    • Scott Adams
      Yes, I meant if you had celiac disease but went gluten-free before screening, your results would end up false-negative. As @trents mentioned, this can also happen when a total IGA test isn't done.
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