Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Positive ANA, Low IGA and IGM, What does everything mean as a whole?

meowmix
 Share

Recommended Posts

meowmix Newbie
meowmix
Posted

Iron: 17 mcg/dL (Low) November 11, 2016

Ferritin: 1.8 ng/mL (Low) November 11, 2016

RBC: 4.05x10^6/uL (Low) November 11, 2016

Hemoglobin: 8.5 gm/dL (Low) November 11, 2016

Vitamin D: 25.7 ng/mL (Low) February 22, 2017

ANA Profile :  February 27, 2017

FANA:  Positive

 FANA Titer: 1:640

FANA Pattern: Homogenous

Gliadin IgA: 2 units June 29, 2017

Gliadin IgG: 3 units June 29,2017

TTG Ab IgA: <1 units/mL June 29, 2017

TTG Ab IgG: <1 units/mL June 29, 2017

Immunoglobulin A:  59.1 mg/Dl (Low) July 10, 2017

Immunoglobulin M: 44.2 mg/Dl (Low) July 10,2017

Immunoglobulin G: 1010.0 mg/Dl (Normal?) July 10, 2017

Immunoglobulin E: 5 KU/L July 10,2017

My RBC and Hemoglobin have come up and are normal.  My iron levels will get high (too high) when I take 65 mg elemental iron twice a day for several weeks but my ferritin has never gotten over 42 ng/mL.  When I stop taking my iron supplement my iron and ferritin plummet in just a matter of weeks.  My hair is falling out, I get rapid heartbeat when I get too low on iron and if I get my iron too high.  My whole body hurts especially my finger joints, back , knees and really all of my joints.  Going to the bathroom at least 2 times day and sometimes up to 5 times a day.   Extreme fatigue, Brain fog, extremely emotional and irritable.  I just went gluten free July 1, 2017 and am starting to feel better.  Joints feel better, I can sleep better, my mood is better.  Celiac or maybe just gluten sensitive?  Any thoughts?  What do my labs say about me?        

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


cyclinglady Grand Master
cyclinglady
Posted
5 hours ago, meowmix said:

Iron: 17 mcg/dL (Low) November 11, 2016

Ferritin: 1.8 ng/mL (Low) November 11, 2016

RBC: 4.05x10^6/uL (Low) November 11, 2016

Hemoglobin: 8.5 gm/dL (Low) November 11, 2016

Vitamin D: 25.7 ng/mL (Low) February 22, 2017

ANA Profile :  February 27, 2017

FANA:  Positive

 FANA Titer: 1:640

FANA Pattern: Homogenous

Gliadin IgA: 2 units June 29, 2017

Gliadin IgG: 3 units June 29,2017

TTG Ab IgA: <1 units/mL June 29, 2017

TTG Ab IgG: <1 units/mL June 29, 2017

Immunoglobulin A:  59.1 mg/Dl (Low) July 10, 2017

Immunoglobulin M: 44.2 mg/Dl (Low) July 10,2017

Immunoglobulin G: 1010.0 mg/Dl (Normal?) July 10, 2017

Immunoglobulin E: 5 KU/L July 10,2017

My RBC and Hemoglobin have come up and are normal.  My iron levels will get high (too high) when I take 65 mg elemental iron twice a day for several weeks but my ferritin has never gotten over 42 ng/mL.  When I stop taking my iron supplement my iron and ferritin plummet in just a matter of weeks.  My hair is falling out, I get rapid heartbeat when I get too low on iron and if I get my iron too high.  My whole body hurts especially my finger joints, back , knees and really all of my joints.  Going to the bathroom at least 2 times day and sometimes up to 5 times a day.   Extreme fatigue, Brain fog, extremely emotional and irritable.  I just went gluten free July 1, 2017 and am starting to feel better.  Joints feel better, I can sleep better, my mood is better.  Celiac or maybe just gluten sensitive?  Any thoughts?  What do my labs say about me?        

What does your doctor say or advise?   I am glad that you are feeling better, we are not doctors and we can not diagnose you.  We can offer you supoort and we sure know a lot about the gluten free diet.   We can definitely help you with that!  

meowmix Newbie
meowmix
Posted
  • Author

I haven't heard back from my doctor yet.  I was just wondering if any of my these labs where common among people with celiac.  Thanks for responding!

cyclinglady Grand Master
cyclinglady
Posted

It seems like you have a lot going on, so it would be best to talk to your doctor.  Lab ranges are missing, so I could not say if your celiac panel is positive or not.  Each lab varies.  Would hate to point you in the wrong direction.  

I can tell you that anemia  was my main symptom.  Doctors all my life blamed menstruation for my iron deficiency and I already had a genetic anemia.  So, I was dismissed.  Find out the real reason as to why you continue to be anemic.   

meowmix Newbie
meowmix
Posted
  • Author

Thanks for responding again.  None of the nurse practitioners or the doctor would ever really say what caused my anemia.  They all kinda thought that it was from heavy periods.  Gosh, you go in to see a doctor or nurse practitioner and they have about 10 minutes to give you before they start backing out the door.  Its kinda no wonder why no one ever gets the whole story or finds out whats really wrong (or why it takes so long to finally figure it out).  It sucks for the patient but it also sucks for the nurses and doctors because they are stretched so thin.  I know what it is like to work when there is too much to do and not enough time or people to do it.  It hurts everyone.  

Hatbox121 Apprentice
Hatbox121
Posted

Have you not been sent to rheumatology to further investigate the positive ANA? A positive ANA alone can't diagnose anything but it does warrant further investigation and more blood work, ie lupus, RA, scleroderma, etc depending on symptomology. 

There is also an anemia of chronic disease which I think can be connected to certain connective tissue disorders.

meowmix Newbie
meowmix
Posted
  • Author

My RA blood test was negative and my dsDNA was negative too.  I think that the dsDNA is the lupus test.  I think.  I haven't been referred to a rheumatologist.   

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Hatbox121 Apprentice
Hatbox121
Posted
16 hours ago, meowmix said:

My RA blood test was negative and my dsDNA was negative too.  I think that the dsDNA is the lupus test.  I think.  I haven't been referred to a rheumatologist.   

No anti-sm(lupus)? Yes, anti dsDNA is for SLE(lupus). No ENA panel,anti-RNP, anti-SS-A, anti-SS-B, anti histone, scl-70, etc? I'd ask for a referral, if you feel that there is something going on. I think that would be a logical step because of the positive ANA and lack of investigation. 1:640 is definitely positive. 

meowmix Newbie
meowmix
Posted
  • Author

SSB <3.3 RLU <=20 (reference range)

RNP <3.5 RLU <=20

Sm <3.3 RLU <=20

SSA Ro52 <2.3 RLU <=20

SSA Ro60 <4.9 RLU <=20

Scl 70 <1.2 RLU <=20

Jo 1 <2.2 RLU <=20

ds DNA Negative

FANA Positive

FANA Titer 1:640

FANA Pattern Homogeneous

 

 

  • 2 years later...
caulodren Newbie
caulodren
Posted

ana+ positive can be positive with seasonal allergies as well, i had a similar problem

pikakegirl Enthusiast
pikakegirl
Posted

I always have a high positive ANA. Diagnosed 13 years ago. Militant gluten free, I don't eat out at all. My thyroid causes many of the symptoms you describe if it is out of my comfort range, which is individual on a large scale of normal. The normal range is to wide and I feel that is why many are not properly diagnosed. My perfect number is 1.5 but I am best going closer to hyper than to hypo. Have you been checked for Hashimotos?

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share
Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      130,190
    • Most Online (within 30 mins)
      7,748
    Sah
    Newest Member
    Sah
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • knitty kitty
      TTG IgA and IGA elevated mildy

      By knitty kitty · Posted

      Hi, @thejayland10, Do you still consume dairy?  Dairy can cause increased tTg IgA levels in some people with celiac disease who react to casein, the protein in dairy, just like to gluten.   You might try cutting out the processed gluten free foods.  Try a whole foods, no carbohydrate Paleo diet instead, like the AIP diet (the Autoimmune Protocol Diet by Dr. Sarah Ballantyne, a Celiac herself). Processed gluten free foods can be full of excess carbohydrates which can alter your microbiome leading to Small Intestinal Bacterial Overgrowth (SIBO).  SIBO is found in some people who are not responding to a gluten free diet.  SIBO can elevate tTg IgA levels.  The AIP diet cuts out sources of carbohydrates like rice, potatoes (nightshades), quinoa, peas, lentils, legumes, which starves out the SIBO bacteria.  Better bacteria can then proliferate.   I followed the AIP diet to get rid of my SIBO.  It's a strict diet, but my digestive tract had time to rest and heal.  I started feeling better within a few days.  Feeling improvement so soon made sticking to the AIP diet much easier. References: Small intestinal bacterial overgrowth among patients with celiac disease unresponsive to a gluten free diet https://pmc.ncbi.nlm.nih.gov/articles/PMC7759221/   Luminal antigliadin antibodies in small intestinal bacterial overgrowth https://pubmed.ncbi.nlm.nih.gov/9260801/#:~:text=Luminal total IgA concentrations (p,response to local bacterial antigens.   Potato glycoalkaloids adversely affect intestinal permeability and aggravate inflammatory bowel disease https://pubmed.ncbi.nlm.nih.gov/12479649/
    • trents
      New to gluten free living, in5ro and small question

      By trents · Posted

      First, welcome to the forum, @boy-wonder! Second, a little clarification in terminology is in order. Granted, inconsistency is rampant when it comes to the terminology associated with gluten disorders, but it has more or less become settled in this fashion: "Gluten intolerance" is a general term that car refer to either celiac disease or NCGS (Non Celiac Gluten Sensitivity). "Gluten Sensitivity" is the shortened version of NCGS. Third, Celiac disease is not an allergy to gluten. It is an autoimmune disorder characterized by gluten ingestion causing the immunes system to attack the lining of the small bowel, causing damage to it over time due to the constant inflammation that wears down the "villi" (mucosal finger-like projections that make up the lining). Over a significant period of time as gluten continues to be consumed, this generally results in impaired nutrient absorption. There are specific blood antibody tests available to check for celiac disease but the testing will not be valid while on a reduced gluten diet or a gluten free diet. Those already having having begun a gluten free diet must go back to consuming generous amounts of gluten for a period of weeks if they wish to pursue testing for celiac disease. Fourth, NCGS shares many of the same symptoms of celiac disease but does not damage the lining of the small bowel as does celiac disease. There is no test for it. A diagnosis for NCGS depends on first ruling out celiac disease. It is 10x more common than celiac disease. Some experts feel it can be a precursor to the development of celiac disease. Eliminating gluten from your life is the antidote for both. Fifth, you state that you are convince you don't have celiac disease by are just "gluten intolerant" (aka, gluten sensitive). How do you know that? It seems to me you are making a dangerous assumption here. I suggest you consider getting formally tested for celiac disease.
    • AllyJR
      Gluten free parakeet food

      By AllyJR · Posted

      Has anyone found a gluten free parakeet seed mix? I can't find a single one! My doctor wants me to make sure all pet food in the house is gluten free but I'm not sure if that's even possible with parakeets. We love our birds so much! I'm wondering if anyone has ever made their own bird seed mix if gluten free ones are not available. 
    • boy-wonder
      New to gluten free living, in5ro and small question

      By boy-wonder · Posted

      Hi, new member. About me, I had been suffering with weight gain, bloating and irregular and extreme bowel habits for a year or so. For example, I went on holiday in 2023, then again I  2024 at the same time of year and every shirt I wore in 2023 didn't fit anymore, couldn't even do the buttons up. Being in my mid 50s I put it down to age and middle aged spread. I'd been lucky all my life having good metabolism and being able to eat anything and as much as I like without putting on any weight, it drove my other half mad. Over a conversation with a friend health and age Related stuff came up and he mentioned someone he knew who had recently found out they were gluten intolerant,  I looked it up and had every one of 8 or so symptoms listed. Bloating,  weight gain,  headaches, brain fog,  constipation, etc etc. I took the decision to give going gluten free a try. Within 1 week I had lost 4 lb, now 7 weeks in I've lost 13 lb. I feel much better in general,  the bloating has severely subsided, it used to keep me awake at night as I felt so uncomfortable.  So pretty much a success story, as everyone here knows,  going gluten free isn't always easy, and eating out can be awkward,  but I consider myself lucky that I appear to have an intolerance rather than an allergy or being celiac.  I can deal with most of the gluten free options at the supermarket but, the big one for me is bread, I love bread, and the gluten free options I've tried are pretty poor. I was at a posh black tie event last night and chose all the food options I thought would be gluten free,  however,  there was bread on the table and I couldn't resist it, I had I small piece of bread,  god it was good, I wanted more but I resisted. Today I feel a bit dodgy, my stomach is churning, and I generally feel a bit urgh.  So here's the question, is that really down to 1 small piece of bread or is it coincidence?  I'd be interested in hearing how other people have reacted to a similar situation,  as I was considering having a day off every now and then and enjoying some lovely fresh bread.
    • ValerieC
      Guide to colleges for celiac disease

      By ValerieC · Posted

      Does anybody know of a guide that ranks reevaluates universities and colleges in terms of their accommodation of celiac disease or food allergies?   Thanks in advance for any leads! Valerie 
×
×
  • Create New...