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Celiac Markers Help

holdthegluten

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holdthegluten Rising Star
holdthegluten
Posted

My brother just recently got tested and they said he had a low IgA. What does this marker represent, as well as the others above......They are now doing a blood test for IgG. Does a low IgA indicate celiac disease.

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Rachel--24 Collaborator
Rachel--24
Posted

If its the total serum IgA thats low it means that he is IgA deficient.

It means that his bloodwork (IgA) will be negative regardless of whether or not he has Celiac Disease.

happygirl Collaborator
happygirl
Posted

These are the tests often run for Celiac:

Anti-gliadin antibodies (AGA) both IgA and IgG

Anti-endomysial antibodies (EMA) - IgA

Anti-tissue transglutaminase antibodies (tTG) - IgA

Total IgA level.

It sounds like he is IgA deficient, which negates the AGA IgA, EMA IgA, and tTG IgA tests. They will probably run the tTG IgG test next.

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