Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Curious About Genetics

jmrogers31

Recommended Posts

jmrogers31 Contributor
jmrogers31
Posted

In the research I have done about Celiac Disease it seems that it affects people of Northern European decent more frequently than others but not exclusively. My Dad's side of the family is Swedish and my Mom's side is Irish and they are both northern European countries. I have had genetic testing and it came back with HLA-DQ 2,3 (Subtype 2,8) which seems to be the main genes associated with Celiac and said both my parents passed the gene to me so I have two copies of each. My question is that do most of you have northern European ancestry or is that kind of a myth. Most of my wife's ancestors are from the Czech Republic which isn't as far north and she has no issues. So, Celiacs what is your ancestry? Are most of you from northern Europe or is that kind of a myth. I am curious to see where these genes come from.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


kareng Grand Master
kareng
Posted

You might find this older thread interesting:

They way people come & go on here, you should get some new entries.

jmrogers31 Contributor
jmrogers31
Posted
  • Author

Thanks Karen. I have been on this site for a year but missed this one. I thought it wasn an interesting thought, but I guess with all the forums and all the people on this site it doesn't surprise me this has been covered already. It's like an episode of South Park where every idea that they came up with has already been done on the Simpsons because after hundreds of episodes of the Simpsons almost everything has been covered.

kareng Grand Master
kareng
Posted

Thanks Karen. I have been on this site for a year but missed this one. I thought it wasn an interesting thought, but I guess with all the forums and all the people on this site it doesn't surprise me this has been covered already. It's like an episode of South Park where every idea that they came up with has already been done on the Simpsons because after hundreds of episodes of the Simpsons almost everything has been covered.

But this place can be a revolving door. Maybe some who didn't post preciously would like to add on?

I saw something that said that the biggest group of Celiacs are from North African descent. It was a reputable source but, I can't find it again! Not sure even what they were counting as N. African descent.

nvsmom Community Regular
nvsmom
Posted

I've heard that same thing about Northern European descent. it seems supported by that like kareng provided. Interesting...

I'm Canadian with a German and Ukranian/Polish background. My family all came over in the early 1900's. I haven't had genetic testing done but there is celiac on the Ukranian/Polish side of the family.

Nicole S

mbrookes Community Regular
mbrookes
Posted

Scotch/Irish on both sides.don't know of anyone else that has Celiac in my family, but I strongly suspect that my Mom did from symptoms I remember.

Victoria6102 Contributor
Victoria6102
Posted

I'm French, Italian, greek, and Scandinavian. I have heard from many people and sources that its most common in Europeans!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Adalaide Mentor
Adalaide
Posted

German/Irish here. Family history suggests my ancestors moved from somewhere in Scandinavia to Germany before coming to America although we haven't been able to confirm that for certain.

nora-n Rookie
nora-n
Posted

Recently they discovered that in parts of northern Aftica, up to 7-8% have celiac, and in the mediterranian countries 1% or more, and in India and Iran also.

Just that they do not get tested because doctors only suspect celiac with northern Europeans.

By the way, there is much celiac in Austria, which is not northern european.

MitziG Enthusiast
MitziG
Posted

Scottish and Irish on my mom's side (she also has Celiac) English and Native American on Dad's side (he probably has celiac, at least is gluten intolerant- never tested)

jmrogers31 Contributor
jmrogers31
Posted
  • Author

Interesting to see everything from Native American to Northern Africa to Ukraine. I guess by this time most of us have had a variety of different nationalities mixed into our genes.

LauraB0927 Apprentice
LauraB0927
Posted

I'm 50% Polish (mom's side) and the rest Irish/German/Scottish (dad)....have no idea what side it came from, as it doesnt seem like anyone in my family has Celiac but me. :(

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. knitty kitty
      - knitty kitty replied to pothosqueen's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      16

      Positive biopsy

      In the study linked above, the little girl switched to a gluten free diet and gained enough weight that that fat pad was replenished and surgery was not needed. Here's the full article link... Superior Mesenteric Artery Syndrome in a 6-Year-Old Girl with Final Diagnosis of Celiac Disease https://pmc.ncbi.nlm.nih.gov/articles/PMC6476019/
    2. knitty kitty
      - knitty kitty replied to Jordan Carlson's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      1

      Fruits & Veggies

      Hello, @Jordan Carlson, So glad you're feeling better. Tecta is a proton pump inhibitor. PPI's also interfere with the production of the intrinsic factor needed to absorb Vitamin B12. Increasing the amount of B12 you supplement has helped overcome the lack of intrinsic factor needed to absorb B12. Proton pump inhibitors also reduce the...
    3. knitty kitty
      - knitty kitty replied to pothosqueen's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      16

      Positive biopsy

      @pothosqueen, Welcome to the tribe! You'll want to get checked for nutritional deficiencies and start on supplementation of B vitamins, especially Thiamine Vitamin B 1. There's some scientific evidence that the fat pad that buffers the aorta which disappears in SMA is caused by deficiency in Thiamine. In Thiamine deficiency, the body...
    4. Scott Adams
      0

      Inmate with Celiac Disease Wins $630,000 After Jail Denies Gluten-Free Food

    5. trents
      - trents replied to pothosqueen's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      16

      Positive biopsy

      Wow! You're pretty young to have a diagnosis of SMA syndrome. But youth also has its advantages when it comes to healing, without a doubt. You might be surprised to find out how your health improves and how much better you feel once you eliminate gluten from your diet. Celiac disease is an autoimmune disorder that, when gluten is consumed, triggers an...
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      133,017
    • Most Online (within 30 mins)
      7,748
    Kayy
    Newest Member
    Kayy
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • knitty kitty
      Positive biopsy

      By knitty kitty · Posted

      In the study linked above, the little girl switched to a gluten free diet and gained enough weight that that fat pad was replenished and surgery was not needed.   Here's the full article link... Superior Mesenteric Artery Syndrome in a 6-Year-Old Girl with Final Diagnosis of Celiac Disease https://pmc.ncbi.nlm.nih.gov/articles/PMC6476019/
    • knitty kitty
      Fruits & Veggies

      By knitty kitty · Posted

      Hello, @Jordan Carlson, So glad you're feeling better.   Tecta is a proton pump inhibitor.  PPI's also interfere with the production of the intrinsic factor needed to absorb Vitamin B12.  Increasing the amount of B12 you supplement has helped overcome the lack of intrinsic factor needed to absorb B12. Proton pump inhibitors also reduce the production of digestive juices (stomach acids).  This results in foods not being digested thoroughly.  If foods are not digested sufficiently, the vitamins and other nutrients aren't released from the food, and the body cannot absorb them.  This sets up a vicious cycle. Acid reflux and Gerd are actually symptoms of producing too little stomach acid.  Insufficient stomach acid production is seen with Thiamine and Niacin deficiencies.  PPI's like Tecta also block the transporters that pull Thiamine into cells, preventing absorption of thiamine.  Other symptoms of Thiamine deficiency are difficulty swallowing, gagging, problems with food texture, dysphagia. Other symptoms of Thiamine deficiency are symptoms of ADHD and anxiety.  Vyvanse also blocks thiamine transporters contributing further to Thiamine deficiency.  Pristiq has been shown to work better if thiamine is supplemented at the same time because thiamine is needed to make serotonin.  Doctors don't recognize anxiety and depression and adult onset ADHD as early symptoms of Thiamine deficiency. Stomach acid is needed to digest Vitamin C (ascorbic acid) in fruits and vegetables.  Ascorbic acid left undigested can cause intestinal upsets, anxiety, and heart palpitations.   Yes, a child can be born with nutritional deficiencies if the parents were deficient.  Parents who are thiamine deficient have offspring with fewer thiamine transporters on cell surfaces, making thiamine deficiency easier to develop in the children.  A person can struggle along for years with subclinical vitamin deficiencies.  Been here, done this.  Please consider supplementing with Thiamine in the form TTFD (tetrahydrofurfuryl disulfide) which helps immensely with dysphagia and neurological symptoms like anxiety, depression, and ADHD symptoms.  Benfotiamine helps with improving intestinal health.  A B Complex and NeuroMag (a magnesium supplement), and Vitamin D are needed also.
    • knitty kitty
      Positive biopsy

      By knitty kitty · Posted

      @pothosqueen, Welcome to the tribe! You'll want to get checked for nutritional deficiencies and start on supplementation of B vitamins, especially Thiamine Vitamin B 1.   There's some scientific evidence that the fat pad that buffers the aorta which disappears in SMA is caused by deficiency in Thiamine.   In Thiamine deficiency, the body burns its stored fat as a source of fuel.  That fat pad between the aorta and digestive system gets used as fuel, too. Ask for an Erythrocyte Transketolace Activity test to look for thiamine deficiency.  Correction of thiamine deficiency can help restore that fat pad.   Best wishes for your recovery!   Interesting Reading: Superior Mesenteric Artery Syndrome in a 6-Year-Old Girl with Final Diagnosis of Celiac Disease https://pubmed.ncbi.nlm.nih.gov/31089433/#:~:text=Affiliations,tissue and results in SMAS.  
    • trents
      Positive biopsy

      By trents · Posted

      Wow! You're pretty young to have a diagnosis of SMA syndrome. But youth also has its advantages when it comes to healing, without a doubt. You might be surprised to find out how your health improves and how much better you feel once you eliminate gluten from your diet. Celiac disease is an autoimmune disorder that, when gluten is consumed, triggers an attack on the villous lining of the small bowel. This is the section of the intestines where all our nutrition is absorbed. It is made up of billions of tiny finger-like projections that create a tremendous surface area for absorbing nutrients. For the person with celiac disease, unchecked gluten consumption generates inflammation that wears down these fingers and, over time, greatly reduces the nutrient absorbing efficiency of the small bowel lining. This can generate a whole host of other nutrient deficiency related medical problems. We also now know that the autoimmune reaction to gluten is not necessarily limited to the lining of the small bowel such that celiac disease can damage other body systems and organs such as the liver and the joints and cause neurological problems.  It can take around two years for the villous lining to completely heal but most people start feeling better well before then. It's also important to realize that celiac disease can cause intolerance to some other foods whose protein structures are similar to gluten. Chief among them are dairy and oats but also eggs, corn and soy. Just keep that in mind.
    • pothosqueen
      Positive biopsy

      By pothosqueen · Posted

      26F!
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.