Yes and no for me. I had a whole list of 40-50 symptoms that went away completely when I went gluten free, some taking days to ease up, others slower and taking weeks to disappear completely.
But it took me a couple months of having some of my pains and some other odd symptoms not ease up, and at times to be worse, for me to figure out that I must also have vitamin deficiencies. Got tested, and sure enough, I had some major ones. Treating them did knock my other major symptoms out.
And I found that I had some new food intolerances that I hadn't had before going gluten-free, so a few more foods were removed from my diet.
But I still have odd issues arise from time to time. Some of it I know is related to the damage that gluten did to various organs that is never going to heal. Some of it I still don't understand and continue to do research all of the time, hoping to avoid major problems in the future.
I think one of the things that I have learned through this process is how much I still don't know simply because I haven't stumbled upon the information yet, and how much the medical community still doesn't know because so little research has been done in this area.