'eat What You Want' Pill Caution
Posted 07 March 2006 - 05:56 PM
'EAT WHAT YOU WANT' PILL CAUTION
The pill makes the gut less ’leaky’ Experts advise caution about claims of a pill that could enable people with diabetes and coeliac disease to eat foods that are normally off-limits.
People with coeliac disease need to avoid wheat and diabetics sugary foods to manage their medical conditions.
Researchers at the University of Baltimore say a pill that makes the gut more watertight could allow these patients to eat whatever they want, says a BBC report.
But the early studies were on rats and experts questioned the implications.
MORE @: http://paktribune.co...x.php?id=136585
Posted 07 March 2006 - 06:09 PM
I sure wouldn't trust my health to any pill that hasn't had at least five or ten years of testing.
Posted 07 March 2006 - 06:48 PM
Aren't there more important things to research than a get-out-of-jail-free card for diabetics and celiacs? It's not a cure, it's like lactaid or something. Only worse. Ephedrine.
We'll all float on, alright
Well we'll float on good news is on the way...
Posted 07 March 2006 - 08:55 PM
The Lord bless you and keep you; the Lord make His face shine upon you and be gracious to you." Numbers 6:24-25
Posted 09 March 2006 - 04:46 AM
"I will try again tommorrow" (Mary Anne Radmacher)
celiac 49 years - Misdiagnosed for 45
Blood tested and repeatedly negative
Diagnosed by Allergist with elimination diet and diagnosis confirmed by GI in 2002
Misdiagnoses for 15 years were IBS-D, ataxia, migraines, anxiety, depression, fibromyalgia, parathesias, arthritis, livedo reticularis, hairloss, premature menopause, osteoporosis, kidney damage, diverticulosis, prediabetes and ulcers, dermatitis herpeformis
All bold resoved or went into remission with proper diagnosis of Celiac November 2002
Some residual nerve damage remains as of 2006- this has continued to resolve after eliminating soy in 2007
Mother died of celiac related cancer at 56
Twin brother died as a result of autoimmune liver destruction at age 15
Children 2 with Ulcers, GERD, Depression, , 1 with DH, 1 with severe growth stunting (male adult 5 feet)both finally diagnosed Celiac through blood testing and 1 with endo 6 months after Mom
Positive to Soy and Casien also Aug 2007
Gluten Sensitivity Gene Test Aug 2007
HLA-DQB1 Molecular analysis, Allele 1 0303
HLA-DQB1 Molecular analysis, Allele 2 0303
Serologic equivalent: HLA-DQ 3,3 (Subtype 9,9)
Posted 09 March 2006 - 09:35 AM
15 year old twins with celiac, diagnosed dec. 2005
11 year old daughter with celiac diagnosed dec 2005
17 year old son with celiac gene
Posted 09 March 2006 - 10:57 AM
Personally, I'd rather stick to a diet that is sure to have no side effects, unless you want to consider being healthy a side effect!
Intolerant to all lectins (including gluten), nightshades (potatoes, tomatoes, peppers, eggplant) and salicylates.
Asperger Syndrome, Tourette Syndrome, Addison's disease (adrenal insufficiency), hypothyroidism, fatigue syndrome, asthma
Posted 09 March 2006 - 01:13 PM
Celiac since 05
egg allergy since 08
Posted 09 March 2006 - 02:35 PM
Posted 09 March 2006 - 03:05 PM
"Life is what happens while you're busy making other plans"
"When people show you who they are, believe them"--Maya Angelou
"Bloom where you are planted"--Bev
Posted 09 March 2006 - 03:09 PM
The gluten-free diet keeps my weight pretty stable and my health good...
If I could have all the "gluten stuff" again, I would gain 30 pounds in the first month -- haha
Posted 10 March 2006 - 03:32 AM
After reading about wheat and how much its changed over 1000's of years (it in no way resembles the plant it use to be) I honestly don't feel its good for anyone. I'm happy with my celiac diet I eat much healthier then I ever did before. But again, if I could use something here and there it would be nice.
I personally think that "soon" medical researchers will learn how to "turn off" our celiac gene. the advances being made in gene research has the potential to fix us. Now the question is: What does soon mean? I don't think it means next year or even 5 years from now, but I do believe its in my lifetime (I'm 51).
Posted 10 March 2006 - 06:59 AM
I would not take it so I could eat a "normal" diet that contained gluten. I would consider it, however, for situations where I could be accidently glutened thru CC. Even then, it would depend on what the side effects were, and anything else I would learn about it.
Exactly.. I would still eat gluten-free, but if wanted to go out to eat ANYPLACE it be nice to have some chance at protection.
- Vincent -
Posted 10 March 2006 - 10:30 AM
In terms of side effects---he said that study participants experienced little to no side effects. He said participants who had the placebo actually had a higher rate of side effects.
In terms of the leaky guy, etc.....it was fascinating to hear him talk about it. I had never fully understood it until I heard him explain it and show pictures. (the pictures probably helped---but they have some on their website that are helpful). I'll try to explain how he presented it.
We have cells that act as barriers. Previously, researchers thought that the connectors between the cells were more like permanent fences, not letting anything through. Based on research by Dr. Fassano at the University of Maryland, they discovered that they are not fences, but more like gates that can open and close. Dr. Fassano identified "zonulin" which they believe is the "gate" opener and closer. Increased zonulin leads to the opening of the gates. In particular, research done by Dr. Fassano has found that Celiac patients have higher levels of zonulin, which "opens" the barriers. When these gates are opened, the gluten gets through. For people with Celiac, then the autoimmune response occurs.
The purpose of the AT-1001 is to stop the overexpression of zonulin, which in effect, would keep the gates closed, therefore not allowing gluten to permeate the gut, which would prevent the autoimmune reaction from ever occurring. The press release is being issued Monday that states that Phase 1 of the actual testing (on non Celiacs and Celiacs) was successful. It prevented the autoimmune reaction from happening. Their hypothesis was supported.
He believes that the leaky gut/zonulin is a key, if not the key, component of many other autoimmune disorders, including Type 1 diabetes, and potentially Rheumatoid Arthritis and MS (and others). Increased levels of zonulin have been found in Type 1 Diabetes patients, as well.
The pill would be taken like a lactaid---with/before meals that may/do contain gluten (as opposed to popping one each morning.)
Hope this helps shed more light on it.
Posted 10 March 2006 - 12:10 PM
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