Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Bacterial Link in Celiac Disease Found


Posterboy

Recommended Posts

Posterboy Mentor

To All,

Did anybody see this new research...It would be nice to see an article about this new research on Celiac.com soon.  It might explain the older research about how the Epstein Barr Virus (EBV) has been associated with a subsequent Celiac diagnosis and other associated auto-immune diseases. I would be nice to hear everybody insight on this new research. Is this the "Elusive" smoking gun?

https://medicalxpress.com/news/2020-01-bacterial-link-celiac-disease.html

Posterboy,


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



trents Grand Master

Very interesting and seems to be another piece of the puzzle. However, it doesn't answer the question of why this only happens with certain genotypes. Presumably, those without the Celiac genes would be exposed to the same bacteria but their immune systems would still be able to differentiate between the bacteria and the grain when encountering the same gluten protein fragment. However, it may answer the question of what triggers the expression of the disease and turns it from the latent form to the active form.

Scott Adams Grand Master

We do plan a summary of this soon. Also, we have been ahead of the curve on this concept:

And they are now looking at this for MS treatments:

 

Posterboy Mentor

Scott,

That is good research the Jamron research I had recently read linked at the bottom of a new thread but I will refresh myself with that information....inflammation is being mentioned more and more these days for disease of all types....I think it is interesting to see the link/connections....I wonder when they will figure out what is triggering celiac disease so it can be cured soon!

Here is the link to the EBV connection and yes MS is linked in their estimation in one of the seven diseases studied as possibly being triggered by a virus...

https://medicalxpress.com/news/2018-04-epstein-barr-virus-linked-diseases.html

I also found where a Candida infection (inflammation again) has also been studied as a possible trigger for Lupus...

https://lupusnewstoday.com/2016/01/13/new-agents-harness-inflammatory-responses-to-fungal-infection/

I hope this is helpful but it is not medical advise.

Posterboy,

  • 1 month later...
nickibeaks Rookie

I got Lyme disease 10 years ago around the time when all of my symptoms really started to crop up. I definitely had symptoms before but not nearly as severe. It took 6 years to get diagnosed and another 2 years to get it treated. I have been thinking about whether Lyme has something to do with Celiac getting so bad 

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      132,206
    • Most Online (within 30 mins)
      7,748

    S.Craigwell
    Newest Member
    S.Craigwell
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • trents
      NCGS does not cause damage to the small bowel villi so, if indeed you were not skimping on gluten when you had the antibody blood testing done, it is likely you have celiac disease.
    • Scott Adams
      I will assume you did the gluten challenge properly and were eating a lot of gluten daily for 6-8 weeks before your test, but if not, that could be the issue. You can still have celiac disease with negative blood test results, although it's not as common:  Clinical and genetic profile of patients with seronegative coeliac disease: the natural history and response to gluten-free diet: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606118/  Seronegative Celiac Disease - A Challenging Case: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441776/  Enteropathies with villous atrophy but negative coeliac serology in adults: current issues: https://pubmed.ncbi.nlm.nih.gov/34764141/  Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.
    • Xravith
      I'm very confused... My blood test came out negative, I checked all antibodies. I suppose my Total IgA levels are normal (132 mg/dl), so the test should be reliable. Still, I'm not relieved as I can't tolerate even a single biscuit. I need to talk to my doctor about whether a duodenal biopsy is necessary. But it is really possible to have intestinal damage despite having a seronegative results? I have really strong symptoms, and I don't want to keep skipping university lectures or being bedridden at home.
    • Scott Adams
      They may want to also eliminate other possible causes for your symptoms/issues and are doing additional tests.  Here is info about blood tests for celiac disease--if positive an endoscopy where biopsies of your intestinal villi are taken to confirm is the typical follow up.    
    • Scott Adams
      In the Europe the new protocol for making a celiac disease diagnosis in children is if their tTg-IgA (tissue transglutaminase IgA) levels are 10 times or above the positive level for celiac disease--and you are above that level. According to the latest research, if the blood test results are at certain high levels that range between 5-10 times the reference range for a positive celiac disease diagnosis, it may not be necessary to confirm the results using an endoscopy/biopsy: Blood Test Alone Can Diagnose Celiac Disease in Most Children and Adults TGA-IgA at or Above Five Times Normal Limit in Kids Indicates Celiac Disease in Nearly All Cases No More Biopsies to Diagnose Celiac Disease in Children! May I ask why you've had so many past tTg-IgA tests done, and many of them seem to have been done 3 times during short time intervals?    
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.