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Bacterial Link in Celiac Disease Found

Posterboy

By Posterboy
in Related Issues & Disorders

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Posterboy Mentor
Posterboy
Posted

To All,

Did anybody see this new research...It would be nice to see an article about this new research on Celiac.com soon.  It might explain the older research about how the Epstein Barr Virus (EBV) has been associated with a subsequent Celiac diagnosis and other associated auto-immune diseases. I would be nice to hear everybody insight on this new research. Is this the "Elusive" smoking gun?

https://medicalxpress.com/news/2020-01-bacterial-link-celiac-disease.html

Posterboy,

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trents Grand Master
trents
Posted

Very interesting and seems to be another piece of the puzzle. However, it doesn't answer the question of why this only happens with certain genotypes. Presumably, those without the Celiac genes would be exposed to the same bacteria but their immune systems would still be able to differentiate between the bacteria and the grain when encountering the same gluten protein fragment. However, it may answer the question of what triggers the expression of the disease and turns it from the latent form to the active form.

Scott Adams Grand Master
Scott Adams
Posted

We do plan a summary of this soon. Also, we have been ahead of the curve on this concept:

And they are now looking at this for MS treatments:

 

Posterboy Mentor
Posterboy
Posted
  • Author

Scott,

That is good research the Jamron research I had recently read linked at the bottom of a new thread but I will refresh myself with that information....inflammation is being mentioned more and more these days for disease of all types....I think it is interesting to see the link/connections....I wonder when they will figure out what is triggering celiac disease so it can be cured soon!

Here is the link to the EBV connection and yes MS is linked in their estimation in one of the seven diseases studied as possibly being triggered by a virus...

https://medicalxpress.com/news/2018-04-epstein-barr-virus-linked-diseases.html

I also found where a Candida infection (inflammation again) has also been studied as a possible trigger for Lupus...

https://lupusnewstoday.com/2016/01/13/new-agents-harness-inflammatory-responses-to-fungal-infection/

I hope this is helpful but it is not medical advise.

Posterboy,

  • 1 month later...
nickibeaks Rookie
nickibeaks
Posted

I got Lyme disease 10 years ago around the time when all of my symptoms really started to crop up. I definitely had symptoms before but not nearly as severe. It took 6 years to get diagnosed and another 2 years to get it treated. I have been thinking about whether Lyme has something to do with Celiac getting so bad 

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      - knitty kitty replied to Hmart's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
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      Is this celiac?

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      Fiber Supplement

      Thanks, that's a great addition that I hadn't thought of.
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      - trents replied to Hmart's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
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      Is this celiac?

      Other diseases, medical conditions, medications and even (for some people) some non-gluten foods can cause villous atrophy. There is also something called refractory celiac disease but it is pretty uncommon.
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      - trents replied to kpf's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
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      ttg iga high (646 mg/dl) other results are normal

      knitty kitty asks a very relevant question. So many people make the mistake of experimenting with the gluten free diet or even a reduced gluten diet soon before getting formally tested.
    5. trents
      - trents replied to Trish G's topic in Gluten-Free Foods, Products, Shopping & Medications
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      Fiber Supplement

      Another great fiber option is dried apricots. Four of them give you 3g of fiber and I find they don't produce all the gas that some other high fiber options do. They taste good too. Costco sells a large bag of them that are labeled gluten-free so you don't have to worry about cross contamination issues like you might in bulk grocery settings.
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    • knitty kitty
      Is this celiac?

      By knitty kitty · Posted

      @Hmart, The reason why your intestinal damage was so severe, yet your tTg IgA was so minimal can be due to cutting back on gluten (and food in general) due to worsening symptoms.  The tTg IgA antibodies are made in the intestines.  While three grams of gluten per day for several weeks are enough to cause gastrointestinal symptoms, ten grams of gluten per day for for several weeks are required to provoke sufficient antibody production so that the antibodies move out of the intestines and into the blood stream where they can be measured in blood tests.  Since you reduced your gluten consumption before testing, the antibody production went down and did not leave the intestines, hence lower than expected tTg IgA.   Still having abdominal pain and other symptoms this far out is indicative of nutritional deficiencies.  With such a severely damaged small intestine, you are not absorbing sufficient nutrients, especially Thiamine Vitamin B 1, so your body us burning stored fat and even breaking down muscle to fuel your body.   Yes, it is a very good idea to supplement with vitamins and minerals during healing.  The eight essential B vitamins are water soluble and easily lost with diarrhea.  The B vitamins all work together interconnectedly, and should be supplemented together.  Taking vitamin supplements provides your body with greater opportunity to absorb them.  Thiamine and the other B vitamins cannot be stored for long, so they must be replenished every day.  Thiamine tends to become depleted first which leads to Gastrointestinal Beriberi, a condition that doctors frequently fail to recognize.  Symptoms of Gastrointestinal Beriberi are abdominal pain and nausea, but neuropathy can also occur, as well as body and joint pain, headaches and more.  Heart rhythm disruptions including tachycardia are classic symptoms of thiamine deficiency.  Heart attack patients are routinely administered thiamine now.   Blood tests for vitamins are notoriously inaccurate.  You can have "normal" blood levels, while tissues and organs are depleted.  Such is the case with Gastrointestinal Beriberi, a thiamine deficiency in the digestive tract.  Eating a diet high in carbohydrates, like rice, starches, and sugar, can further deplete thiamine.  The more carbohydrates one eats, the more thiamine is required per calorie to turn carbs into energy.  Burning stored fats require less thiamine, so in times of thiamine shortage, the body burns fat and muscles instead.  Muscle wasting is a classic symptoms of thiamine deficiency.  A high carbohydrate diet may also promote SIBO and/or Candida infection which can also add to symptoms.  Thiamine is required to keep SIBO and Candida in check.   Thiamine works with Pyridoxine B 6, so if Thiamine is low and can't interact with Pyridoxine, the unused B 6 accumulates and shows up as high.   Look into the Autoimmune Protocol diet.  Dr. Sarah Ballantyne is a Celiac herself.  Her book "The Paleo Approach" has been most helpful to me.  Following the AIP diet made a huge improvement in my symptoms.  Between the AIP diet and correcting nutritional deficiencies, I felt much better after a long struggle with not feeling well.   Do talk to your doctor about Gastrointestinal Beriberi.  Share the article linked below. Thiamine, gastrointestinal beriberi and acetylcholine signaling https://pmc.ncbi.nlm.nih.gov/articles/PMC12014454/ Keep us posted on your progress!
    • Trish G
      Fiber Supplement

      By Trish G · Posted

      Thanks, that's a great addition that I hadn't thought of. 
    • trents
      Is this celiac?

      By trents · Posted

      Other diseases, medical conditions, medications and even (for some people) some non-gluten foods can cause villous atrophy. There is also something called refractory celiac disease but it is pretty uncommon.
    • trents
      ttg iga high (646 mg/dl) other results are normal

      By trents · Posted

      knitty kitty asks a very relevant question. So many people make the mistake of experimenting with the gluten free diet or even a reduced gluten diet soon before getting formally tested.
    • trents
      Fiber Supplement

      By trents · Posted

      Another great fiber option is dried apricots. Four of them give you 3g of fiber and I find they don't produce all the gas that some other high fiber options do. They taste good too. Costco sells a large bag of them that are labeled gluten-free so you don't have to worry about cross contamination issues like you might in bulk grocery settings.
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