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Dh?


redheadheather

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redheadheather Explorer

Do you have to have a complete "outbreak" of DH to be tested for it? I believe DS has/had it (he is + for gluten intolerance).

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frenchiemama Collaborator

The way understand it, the IgA deposits remain in the skin for months or even years after going gluten-free. So they should still be able to take a biopsy.

lovegrov Collaborator

My understanding is that you have to have an active outbreak before they can take a biopsy sample.

richard

frenchiemama Collaborator

Well, I've been looking it up and everything I find says that the biopsy should be taken from normal skin but nothing specifies whether or not there needs to be an active breakout. You should probably talk to a doctor to find out for sure, but if you're interested here are a couple of articles that I found:

"Dermatitis herpetiformis is diagnosed by a special skin test. A very small piece of skin is taken under a local anaesthetic as an outpatient procedure. The test is carried out on skin NOT affected by the rash."

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"The diagnosis of DH is made by a simple skin test. A small piece of skin approximately 3 mms in diameter is taken from an unaffected area, ie. normal looking skin. The skin is examined for the presence of a substance called IgA (immunoglobulin A) and is found at a specific site in the skin. Although the test is simple, it is important a laboratory experienced in the procedure undertakes the examination of the skin. "

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Hope that helps.

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    • trents
      This kind of question is always difficult to give a definitive answer to because of so many variables. One such variable is the sensitivity of the individual celiac to small amounts of gluten cross contamination. An amount that causes a reaction in one celiac many not in another, or at least not be discernable which, of course, does not exactly equate to being "safe".
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      Welcome to the forum, @Mmoc! Please include the reference ranges for the IGA and the TTG tests in your next post if you have access to them. We cannot comment much otherwise as different labs use different reference ranges for these tests and also different units of measurement. There are no universal standards as of yet so the raw test numbers are not always helpful. Having said that, if your IGA (what we usually call "total IGA") is low, the TTG-IGA score will be skewed and cannot be trusted. Other kinds of tests for celiac disease would need to be run, particularly those in the IGG family of tests. Perhaps this will be helpful:  
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