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- Scott Adams replied to Gliadingoaway's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms2Biopsy confirmed no celiac, low gliadin igg but high gliadin iga?
Your situation is intriguing—while the biopsy ruled out celiac disease, the elevated gliadin IgA (along with gastritis from H. pylori) suggests your immune system is reacting to gluten, albeit differently than in classic celiac. High gliadin IgA can occur in non-celiac gluten sensitivity (NCGS), other autoimmune conditions, or even as part of gut inflammation f... -
- Scott Adams replied to Redlima's topic in Related Issues & Disorders2
SSRI stopped working after gluten free diet due to Celiac diag
Your experience highlights a fascinating and often overlooked connection between gut health, mental health, and medication efficacy—something many in the celiac community encounter. When you removed gluten, your body likely began healing, which can dramatically alter nutrient absorption, inflammation levels, and even neurotransmitter production (like serotonin, ... -
- Scott Adams replied to daniellelawson2011's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms3
Lab results
While your negative tTG-IgA result suggests celiac disease is unlikely, the elevated total IgA (638) is notable and warrants further investigation. High IgA can occur in various conditions, including chronic infections, autoimmune disorders (like lupus or rheumatoid arthritis), or even liver disease—but it’s not typically linked directly to MS. That said, yo... -
- Scott Adams replied to nanny marley's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms3
Help needed
Let us know how it goes! Good luck! -
- Scott Adams replied to SophiesMom's topic in Gluten-Free Foods, Products, Shopping & Medications2
Wheat Straw Dishes
PS - To be on the safe side, I would still avoid these products. BTW, there is also a long running debate about whether strawberries are contaminated with gluten when wheat straw is used under the plants, which is a common farming practice for a variety of reasons.
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By Scott Adams · Posted
Your situation is intriguing—while the biopsy ruled out celiac disease, the elevated gliadin IgA (along with gastritis from H. pylori) suggests your immune system is reacting to gluten, albeit differently than in classic celiac. High gliadin IgA can occur in non-celiac gluten sensitivity (NCGS), other autoimmune conditions, or even as part of gut inflammation from H. pylori. Since active gastritis can disrupt the intestinal barrier ("leaky gut"), gluten might trigger temporary immune reactions that could calm post-recovery. The fact that you tolerated gluten accidentally doesn’t necessarily rule out sensitivity; symptoms can be delayed or cumulative. To clarify, consider retesting gliadin IgA after fully treating the H. pylori and healing your gut (ask your doctor about timing). If levels normalize, you may cautiously reintroduce gluten. If they stay high, NCGS or another immune trigger (like cross-reactivity with other foods) could be at play. For now, focus on healing the gastritis—your gluten tolerance may improve as your gut does! -
By Scott Adams · Posted
Your experience highlights a fascinating and often overlooked connection between gut health, mental health, and medication efficacy—something many in the celiac community encounter. When you removed gluten, your body likely began healing, which can dramatically alter nutrient absorption, inflammation levels, and even neurotransmitter production (like serotonin, which SSRIs target). This shift might explain why your SSRI seemed to "stop working"—your gut wasn’t processing the medication (or nutrients critical for mood regulation) the same way it did pre-diagnosis. Switching to an NDRI (which works on dopamine/norepinephrine instead of serotonin) may have bypassed this issue, hence your improvement. As for CBT, it’s absolutely worth exploring! While therapy won’t fix the biochemical side of celiac, it can be invaluable for managing the psychological toll of a major diet overhaul—grief over food restrictions, anxiety about cross-contamination, or the stress of recalibrating your body’s responses. Many celiac patients benefit from CBT to reframe unhelpful thought patterns and build resilience. You might also ask your doctor about checking key nutrient levels (B12, folate, vitamin D, zinc, etc.), as deficiencies post-celiac diagnosis can mimic or worsen mood symptoms. You’re not alone in this; the gut-brain axis is powerful, and your insight into these changes is a huge step toward balancing both. -
By Scott Adams · Posted
While your negative tTG-IgA result suggests celiac disease is unlikely, the elevated total IgA (638) is notable and warrants further investigation. High IgA can occur in various conditions, including chronic infections, autoimmune disorders (like lupus or rheumatoid arthritis), or even liver disease—but it’s not typically linked directly to MS. That said, your brain MRI findings (white matter lesions at 44) and MS-like symptoms are concerning and should absolutely be prioritized with your neurologist. MS and celiac are distinct conditions, though both involve immune dysregulation; some studies hint at a slightly higher risk of autoimmune comorbidities in celiac patients, but no strong evidence ties IgA elevation specifically to MS. Given your symptoms, ruling out MS through neurological evaluation (possibly including a lumbar puncture or additional imaging) is wise. The IgA spike could also align with IBS or another inflammatory process, so collaborating with both your PCP and neurologist to explore all angles—perhaps even a rheumatology consult—might help piece this puzzle together. Wishing you clarity and answers after your upcoming appointment, and hoping you’re one step closer to effective management! -
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By Scott Adams · Posted
PS - To be on the safe side, I would still avoid these products. BTW, there is also a long running debate about whether strawberries are contaminated with gluten when wheat straw is used under the plants, which is a common farming practice for a variety of reasons.
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