Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Interesting Article On Gluten/casein Sensitivity


CMCM

Recommended Posts

CMCM Rising Star

I found this article...kind of thought-provoking overall. After reading the info on celiac and Ireland, and also the link the schizophrenia, I have to wonder about my father in law, who was Irish and schizophrenic.

_________

One of the deep mysteries of our time is the question of why, with living standards higher than ever before in history, so many people in the “developed” world are disabled by chronic fatigue syndrome, depression, ADD, autism, irritable bowl syndrome, psoriasis, hyperactivity and related disorders. The numbers are startling, showing significant jumps, for example, in depression for each age cohort born after World War II.

Americans now in their seventies came of age during the Great Depression and World War II, with great attendant social and emotional trauma. But they had very few depressive illnesses. Baby boomers, born to great prosperity and opportunity, suffered so much affective disorder that their ill fated attempts to live better through chemistry launched a drug culture. And Gen-X’ers (as the boomers’ children call themselves) have taken depressive and affective disorders exponential.

Hyperactivity is a disorder not yet 30 years old, but already some 20% or more of school children are deemed to have it. “Chronic fatigue syndrome” came into being right alongside “yuppie”, (remember it used to be the yuppie flu?) in the 1980’s. And ADD is really a 90’s thing. It would be nice to think that Ciba Geigy created it in order to sell Ritalin, but unfortunately that’s hardly the case. A lot of kids and grownups are seriously afflicted with “brain fog.”

An intriguing new theory on the cause of this epidemic of misery implicates evolutionary biology, modern medical miracles and industrialized food production. In its essence the theory proposes that, for very complex reasons, our basic foodstuffs may be slowly poisoning us.

Casein and gluten, proteins in milk and grain, have a strikingly similar molecular structure. Research underway at university medical centers worldwide indicates that certain individuals, particularly those from Ireland, and Scotland, and their descendants in places like Canada, may be so sensitive to these compounds that dietary overloads can damage the digestive tract and, eventually, the central nervous system.

Dietary gluten is already recognized as the cause of celiac disease. But new research points to gluten intolerance as a possible causative agent of schizophrenia, autism, multiple sclerosis and depression. Dr. Kalle Reichelt of the Institute of Pediatric Research at the University of Oslo in Norway cited over 200 international scholarly sources in a 1996 paper advancing the theory that schizophrenia and related affective disorders are caused by “food constituents (gluten and casein) (that) may have disease-promoting effects and cause behavioral changes.”

The theory originated in the 1960’s with an American, Dr. Curtis Dohan. He put schizophrenics on gluten-free, casein free diets under double blind conditions and got dramatic results. Many of his patients were able to return home from locked mental hospital wards.

Later studies provided conflicting information, but Dohan, who began his investigations because he knew of mental disturbance in celiac disease, argued that other researchers gave up too soon. Because damaged intestinal mucosa must be given time to heal, Dohan said, the diet should be maintained for at least six months before results are assessed.

Reichelt, in Norway, has recently used new methodology to validate Dohan’s theory. Reichelt achieved dramatic learning and behavior improvements in autistic children with a gluten-casein free diet.

According to Reichelt and others, individuals who lack the ability to completely digest gluten and casein end up with errant biologically active peptides in the intestine and the bloodstream. These peptides damage the intestinal wall, setting the stage for food allergies and malabsorption/ malnutrition syndromes. Stress and other factors play various roles, but some gluten and casein peptides get through the blood brain-barrier and disrupt normal brain function.

Reichelt and others found incompletely digested proteins in the urine of children with behavioral disorders. Apparently these “nasty proteins”, gluten and casein, are “opioids”, similar to morphine. They cause havoc in the brain by competing for endorphin (read “feel good”) receptors.

The body responds to these “foreign invaders” as if they were viral, with an inflammatory response, according to the theory. But there is no virus, so the body attacks itself. Over time the central nervous system is damaged, possibly setting the stage for degenerative diseases such as multiple sclerosis. How does this become a disease of modern civilization?

Rice, millet, sorghum, tubers and corn, the foods of the third world, do not contain gluten. But industrialized societies, in the late 20th century, consume primarily wheat, a gluten-containing grain. The practice of cultivating gluten grains (wheat, barley, oats, and rye) began 10,000 years ago in the Middle East and slowly spread through Europe, finally reaching Ireland in 3000 BC. Even today, high rates of celiac disease and schizophrenia in western Ireland hint that many have not fully adapted to glutens.

And, over the past 200 years, humans have fiddled with genetic selection of wheat, greatly enriching its gluten content. Today 50% of the protein in wheat is gluten, a characteristic that facilitates bread baking and adapts the grain well to cultivation and harvesting. Is this a cautionary tale about the unexpected consequences of genetically engineered foods?

Reichelt feels that our diverse modern diet, which relies less on grain than it did even 100 years ago (remember porridge?) results in slow degenerative diseases in sensitive individuals. Chronic depression, chronic fatigue syndrome, ADD, hyperactivity, and other “affective disorders”, may be mixed or hybrid forms, “subsets” of the major neurological disturbances that researchers identify with gluten-casein sensitivity.

But why the sudden “ramping up” of diseases like depression in the past 50 years? Maybe the infection-prone babies whose lives were saved by antibiotics since World War II became the depressed, fatigued and anxious adults of the 90’s. If gluten/casein sensitivity was the underlying cause of a child’s immune problems, one could theorize that it might underly later bouts of depression, ADD, hyperactivity, etc. Today’s senior citizens, on the other hand, survived a time when, typically, vulnerable babies didn’t make it to adulthood.

Perhaps 25 years from now people will say; “Can you imagine, they had no idea that wheat and milk could affect brain function? And all those people sleeping on their streets and filling up their prisons!” It seems foolish… but, then,… it wasn’t so long ago that germ theory and handwashing emerged to save the lives of millions of women who otherwise would have died in childbirth.

THE GLUTEN & DAIRY FREE DIET

DON’T EAT

Cow’s milk in any form….no cheese, no milk, no yogurt, no ice cream, no butter. What you are doing here is avoiding casein, the protein in cow’s milk…lactose free products don’t address the problem of casein intolerance. The one exception to this rule found is ghee or clarified butter. Because the process involved in making ghee, which is clarified butter, involves removing the milk proteins, it appears that this form of butter is acceptable. It is probably a healthier food than hydrogenated margarines, so this has been good news.

ALSO DON’T EAT

Gluten in any form…this means anything made from the gluten grains, wheat rye, oats and barley. Also no kamut, spelt, as these are also gluten grains. This rules out most commercial breads, pastas and most commercial baked goods. Also Chinese noodles and anything that is breaded (like “fish n’ chips” ) before frying are gluten foods. But rice pasta is great…most Thai food is O.K. because their cuisine emphasizes rice noodles Hidden glutens occur in imitation crab (as in California roll sushi), in soy sauce (substitute wheat free tamari sauce), in packaged foods containing hydrolyzed vegetable protein and malt extracts (Sorry, this includes beer).

O.K. TO EAT

All fruits

All vegetables

All eggs

All meats

All fish

All beans

Corn

Rice

Potatoes

Quinoa

Buckwheat

Amaranth

Coffee, tea, wine, brandy


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



danikali Enthusiast

How do I know if I'm casein intolerant? I've been going on and off the dairy for a few weeks now and have not noticed any major changes, if any at all.....but on the other hand, I don't want to be sacrificing my immune system only sticking to the gluten free diet but eating casein! I'm kind of scared here because I've had SEVERE depression before, and if casein can cause that, and I'm sensitive to it, then I'll def. stay away from it. But if it doesn't affect me like the gluten, then I don't want to deprive myself more than I already am! My cravings for dairy are insane when I go off of it and I end up overeating everything else! Any advice?

nettiebeads Apprentice

Thank you very much for the time and effort you put in to your research. You definitely get a gold star for today! :)

Annette

Mango04 Enthusiast
How do I know if I'm casein intolerant? I've been going on and off the dairy for a few weeks now and have not noticed any major changes, if any at all.....but on the other hand, I don't want to be sacrificing my immune system only sticking to the gluten free diet but eating casein! I'm kind of scared here because I've had SEVERE depression before, and if casein can cause that, and I'm sensitive to it, then I'll def. stay away from it. But if it doesn't affect me like the gluten, then I don't want to deprive myself more than I already am! My cravings for dairy are insane when I go off of it and I end up overeating everything else! Any advice?

I've read that you crave the foods you are intolerant and/or allergic to. Maybe you could try to remain completely 100% casein free for atleast a month (maybe longer) and then reintroduce it and see if you notice any differences. I think it's hard to tell what's really happening when you go on and off it - I believe you need to stay CF for a pretty significant amount of time for a self diagnosis to work (that's my experience anyway). Your cravings might subside once the casein has completely left your system. Maybe you could try Enterolab if you're still unsure?

Nancym Enthusiast

I wonder if the high rate of food intolerances is because there was a period where doctors were encouraging women to NOT breastfeed. In fact, my own mother didn't breastfeed any of us because doctors were telling them that formula was healthier. *sigh*

Nevadan Contributor
I found this article...kind of thought-provoking overall. After reading the info on celiac and Ireland, and also the link the schizophrenia, I have to wonder about my father in law, who was Irish and schizophrenic.

Carole,

A very interesting article. Could you please post it's source? Thanks.

George

Claire Collaborator

I found this article...kind of thought-provoking overall. After reading the info on celiac and Ireland, and also the link the schizophrenia, I have to wonder about my father in law, who was Irish and schizophrenic.

_________

Thanks for this post. Did you get it from the internet? If so do you have a URL for it? Thanks. Claire


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



CMCM Rising Star
How do I know if I'm casein intolerant? I've been going on and off the dairy for a few weeks now and have not noticed any major changes, if any at all.....but on the other hand, I don't want to be sacrificing my immune system only sticking to the gluten free diet but eating casein! I'm kind of scared here because I've had SEVERE depression before, and if casein can cause that, and I'm sensitive to it, then I'll def. stay away from it. But if it doesn't affect me like the gluten, then I don't want to deprive myself more than I already am! My cravings for dairy are insane when I go off of it and I end up overeating everything else! Any advice?

Well, my feeling from my own experience was that I had major and identifiable trouble with dairy my entire life. So finding out I was casein intolerant wasn't a surprise. If you don't have symptoms, it may not be an issue for you. It's not for everyone. My mom had the worse possible, classic case of celiac and nearly died before she was diagnosed....and she does not appear to have any problems whatsoever with dairy and never has.

As for testing, you can get it done via Enterolab. I did their complete panel which tested not only the genes, but the celiac/gluten sensitivity, and also for casein thrown in as well. I believe you can do the casein one separately, too. You'd have to check with Enterolab.

Carole

arial12bold Rookie

I think the article comes from this website >> Open Original Shared Link

The homepage is this >> Open Original Shared Link

arial

Archived

This topic is now archived and is closed to further replies.

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      133,243
    • Most Online (within 30 mins)
      7,748

    Maya Baum
    Newest Member
    Maya Baum
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Upcoming Events

  • Posts

    • knitty kitty
      Welcome to the forum, @McKinleyWY, For a genetic test, you don't have to eat gluten, but this will only show if you have the genes necessary for the development of Celiac disease.  It will not show if you have active Celiac disease.   Eating gluten stimulates the production of antibodies against gluten which mistakenly attack our own bodies.  The antibodies are produced in the small intestines.  Three grams of gluten are enough to make you feel sick and ramp up anti-gluten antibody production and inflammation for two years afterwards.  However, TEN grams of gluten or more per day for two weeks is required to stimulate anti-gluten antibodies' production enough so that the anti-gluten antibodies move out of the intestines and into the bloodstream where they can be measured in blood tests.  This level of anti-gluten antibodies also causes measurable damage to the lining of the intestines as seen on biopsy samples taken during an endoscopy (the "gold standard" of Celiac diagnosis).   Since you have been experimenting with whole wheat bread in the past year or so, possibly getting cross contaminated in a mixed household, and your immune system is still so sensitized to gluten consumption, you may want to go ahead with the gluten challenge.   It can take two years absolutely gluten free for the immune system to quit reacting to gluten exposure.   Avoiding gluten most if the time, but then experimenting with whole wheat bread is a great way to keep your body in a state of inflammation and illness.  A diagnosis would help you stop playing Russian roulette with your and your children's health.      
    • trents
      Welcome to the celiac.com community, @McKinleyWY! There currently is no testing for celiac disease that does not require you to have been consuming generous amounts of gluten (at least 10g daily, about the amount in 4-6 slices of wheat bread) for at least two weeks and, to be certain of accurate testing, longer than that. This applies to both phases of testing, the blood antibody tests and the endoscopy with biopsy.  There is the option of genetic testing to see if you have one or both of the two genes known to provide the potential to develop celiac disease. It is not really a diagnostic measure, however, as 30-40% of the general population has one or both of these genes whereas only about 1% of the general population actually develops celiac disease. But genetic testing is valuable as a rule out measure. If you don't have either of the genes, it is highly unlikely that you can have celiac disease. Having said all that, even if you don't have celiac disease you can have NCGS (Non Celiac Gluten Sensitivity) which shares many of the same symptoms as celiac disease but does not involve and autoimmune reaction that damages the lining of the small bowel as does celiac disease. Both conditions call for the complete elimination of gluten from the diet. I hope this brings some clarity to your questions.
    • McKinleyWY
      Hello all, I was diagnosed at the age of 2 as being allergic to yeast.  All my life I have avoided bread and most products containing enriched flour as they  contain yeast (when making the man made vitamins to add back in to the flour).  Within the last year or so, we discovered that even whole wheat products bother me but strangely enough I can eat gluten free bread with yeast and have no reactions.  Obviously, we have come to believe the issue is gluten not yeast.  Times continues to reinforce this as we are transitioning to a gluten free home and family.  I become quite ill when I consume even the smallest amount of gluten. How will my not having consumed breads/yeast/gluten for the better part of decades impact a biopsy or blood work?  I would love to know if it is a gluten intolerance or a genetic issue for family members but unsure of the results given my history of limited gluten intake.   I appreciate the input from those who have gone before me in experience and knowledge. Thank you all!
    • trents
      I know what you mean. When I get glutened I have severe gut cramps and throw up for 2-3 hr. and then have diarrhea for another several hours. Avoid eating out if at all possible. It is the number one source of gluten contamination for us celiacs. When you are forced to eat out at a new restaurant that you are not sure is safe, try to order things that you can be sure will not get cross contaminated like a boiled egg, baked potatos, steamed vegies, fresh fruit. Yes, I know that doesn't sound as appetizing as pizza or a burger and fries but your health is at stake. I also realize that as a 14 year old you don't have a lot of control over where you eat out because you are tagging along with others or adults are paying for it. Do you have support from your parents concerning your need to eat gluten free? Do you believe they have a good understanding of the many places gluten can show up in the food supply?
    • Peace lily
      Okay went online to check green mountain k cups .It was said that the regular coffees are fine but they couldn’t guarantee cross contamination.with the flavors. im trying to figure out since I eliminated the suyrup so far so good. I’m hoping. thanks it feels good to listen to other people there views.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.