Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Alvine Pharmaceuticals Reports Positive Results


patriceo15

Recommended Posts

patriceo15 Rookie

Found this today So I wanted to share with all of you.

Open Original Shared Link


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



darlindeb25 Collaborator

I had read this earlier and I think it's wonderful for accidental glutenings. I however, do not feel it's safe for a celiac/gluten intolerant to feel it's ok to use this type of med and then go ahead and eat gluten. We will never beable to safely eat gluten. There is much testing to be done to prove this type of product...years and years, in my opinion.

ShayFL Enthusiast

I personally will never take a drug when a healthy dietary change cures me. All drugs have side effects and some arent known for years and can be horrible (liver failure, heart failure, etc.) Why on Earth would I take something that could ultimately destroy my health when living gluten-free is very doable and healthy?

happygirl Collaborator

Thanks for sharing this, patrice. Great to see research being done on Celiac.

Puddy Explorer

Thanks, Patrice. This sounds like good news to me!

ENF Enthusiast

It's great news for those of us who would like protection against cross-contamination. Many people with Celiac will want it, even if just for eating out in restaurants or at someone else's house. Bring it on!

Gemini Experienced
Found this today So I wanted to share with all of you.

Open Original Shared Link

The outcome of the Phase 1 Trial of ALV003 is a major step toward providing people with celiac disease a better quality of life, as there are currently no approved pharmaceutical therapies available," said Dr. Ciaran P. Kelly, Medical Director of the Celiac Center at Beth Israel Deaconess Medical Center and Harvard Medical School. "Given the difficulty of following a strict gluten free diet, and the potentially serious health consequences of gluten exposure, there is a great medical need for ALV003 and other new therapies targeting celiac disease."

As much as I think this or any drug would be useful for travellers who want to protect themselves against CC in a foreign country, this statement makes me cringe.

I have wonderful quality of life, as far as food goes and certainly do not need any pharmaceutical therapies, i.e. DRUGS, to make my life better on a daily basis.

We have become such a pill popping nation that most ignore bad eating habits and inactivity and run to a doctor to get a pill for everything. I'm waiting for a pill that breathes for you so you won't have to waste a muscle contraction and the resultant energy it would require. :P No wonder Type 2 diabetes is at epidemic levels!

The diet is also NOT difficult, either. With doctor's going around with that attitude, no wonder people cannot accept a diagnosis and continue to cheat and make themselves sick. I am glad there may be a pill to protect you while travelling but as for use on a daily basis, NOT!


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Archived

This topic is now archived and is closed to further replies.

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      132,805
    • Most Online (within 30 mins)
      7,748

    lovinlifeafter60
    Newest Member
    lovinlifeafter60
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Upcoming Events

  • Posts

    • xxnonamexx
      What about digestive enzymes that I hear help? I take align 5x probiotics daily.
    • Samanthaeileen1
      thank you RMJ! That is very helpful advice. Good to know we aren’t crazy if we don’t do the endoscopy. We are going to try the gluten free and see how symptoms and levels improve.    thank you Wheatwacked (love the username lol) that is also reassuring. Thankfully she has an amazing and experienced pediatrician. And yesss I forgot to mention the poop! She has the weirdest poop issues.    How long did it take y'all to start seeing improvement in symptoms? 
    • Wheatwacked
      My son was diagnosed when he was weaned in 1976 after several endoscopies.  Given your two year old's symptoms and your family history and your pediatrition advocating for the dx, I would agree.  Whether an endoscopy is positive or negative is irrelevant.   That may happen even with endoscopy.  Pick your doctors with that in mind. In the end you save the potential trauma of the endoscopy for your baby.   Mine also had really nasty poop.  His doctor started him on Nutramigen Infant because at the time it was the only product that was hypo allergenic and had complete nutrition. The improvement was immediate.
    • RMJ
      So her tissue transglutaminase antibody is almost 4x the upper end of the normal range - likely a real result. The other things you can do besides an endoscopy would be: 1.  Genetic testing.  Unfortunately a large proportion of the population has genes permissive for celiac disease, but only a small proportion of those with the genes have it. With family history it is likely she has the genes. 2.  Try a gluten free diet and see if the symptoms go away AND the antibody levels return to normal. (This is what I would do). Endoscopies aren’t always accurate in patients as young as your daughter. Unfortunately, without an endoscopy, some doctor later in her life may question whether she really has celiac disease or not, and you’ll need to be a fierce mama bear to defend the diagnosis! Be sure you have a good written record of her current pediatrician’s diagnosis. Doing a gluten challenge for an endoscopy later in life could cause a very uncomfortable level of symptoms.   Having yourself, your husband and your son tested would be a great idea.  
    • Samanthaeileen1
      here are the lab ranges.  Normal ranges for tissue transglutaminase are: <15.0 Antibody not detected > or = 15.0 Antibody detected normal for endomysial antibody is < 1.5. So she is barely positive but still positive. 
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.