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New, Here Are My Labs...


sue1234

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sue1234 Rookie

I have SEVERE abdominal bloating. I twist and turn to get burps up. I get sooo short of breath when I am having a severe bloating episode. Does that sound like a typical celiac symptom??? Does it get that bad for others?? I get so bloated, I look 7 months pregnant.

I had labs done and just had an endoscopy done, where the doctor said everything looked "good". I did have multiple biopsies done and will probably hear back on those by the end of this week. I had all these tests done, with results:

IgG 1219 (700-1600)

IgA 132 (70-400)

IgM 46 (40-230)

Deaminated Gliadin Abs, IgA 45.4(0-10)

"" "" "" , IgG 1.0 (0-10)

Carbohydrate Antigen 19-9 11 (0-35)

tTG (IgA) 0 (0-3)

tTG (IgG) 1 (0-3)

From what I've read, the "big" test is the tTG, and I showed negative. However, I did show positive for the gliadin. Anyone speculate what that means?


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Jean'sBrainonGluten Newbie

sue1234

There is a huge variability in the symptoms people have so yours may or may not be from celiac. If I understand right each of these tests measure different parts of your body reacting and there are different subtypes of gliadins in different types of wheat. Since you've already done the testing you could try a gluten free diet or even a multiple food elimination diet for a couple weeks and see if that helps. Even if it seems not to help you will want to pay attention to how you feel when you reintroduce wheat and other foods after eliminating them for awhile. It isn't unusual to have sensitivities to several foods, especially when first diagnosed. Hope this helps.

Lynayah Enthusiast

I have high Gliadin, but everything else negative (Gliadin in the 80's), which gave me the diagnosis of non-celiac gluten-intolerant. I am very, very sensitive to gluten (see symptoms in my signature).

There is good reading about this in a book entitled HEALTHIER WITHOUT WHEAT. You may want to read it -- it helped me understand a little better.

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    • Scott Adams
      I would pressure the lab to do the IgA control test for free so that you won't write a poor review about their testing services. You could get this done at any time, whether or not you are gluten-free, however, the celiac disease Tissue Transglutaminase tTG-IgA test must be done after you've been eating lots of gluten for around 6 weeks. This way you could salvage the results of your tTG-IgA test, as long as you were eating lots of gluten beforehand.
    • Scott Adams
      Given your strong reactions it would be wise not to eat things offered to you without reading the ingredient labels. It's possible there was indeed gluten or some allergen in the chocolates--barley malt is a common ingredient in some chocolates.
    • trents
      Yes, an IgG panel is the logical next step. However, you would still need to be consuming normal amounts of gluten to ensure valid IgG testing. Since it has only been a week that you have been off gluten, there is still likely time to restore antibodies to detectable levels before the blood draw. IgG antibody tests are not quite as specific for celiac disease as are the IGA tests but they are certainly valuable in the case of IGA deficiency. They also seem to have a little more "staying power" in the sense of detecting celiac disease in the case of those who may have already started a gluten-free diet as long as they haven't been on it for an extended period of time. But don't rely on that. Get back on gluten if you can possibly endure it if you intend to go forward with IgG testing. This might be helpful:   
    • SEQ
      Thanks @trents. I have exchanged some messages with the clinic today, and they are saying that the reason there is no result for the total IgA levels is because I don't have any. Apparently a negative result means that it does not appear as a line on the results at all. I am not sure I buy this, but it is what they are telling me. I am leaning more towards the theory that they didn't test it in the first place. But, working on the basis that the test result was zero, I asked what the next steps would be, given that I apparently have no IgA antibodies. They have asked if I now want to have a tTG-IgG and a DGP-IgG test. Is this really the next step if I have no total IgA?
    • trents
      IGA deficiency is a lot more common than we used to think but I can't give you a number. Doctors used to believe it only happened in children but we know better now. Every doctor should order, at the very minimum, total IGA and tTG-IGA. It may be true that you don't have to worry as much about cross contamination if you have NCGS but that is not a given. By the way, welcome to the forum, @SEQ!
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