Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Can Everyone Post Their Genes

confused

Recommended Posts

confused Community Regular
confused
Posted

Ok I have been intrigued with the celiac and gluten genes. So i was hoping everyone can post their genes.

paula

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


confused Community Regular
confused
Posted
  • Author

Here are mine

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

confused Community Regular
confused
Posted
  • Author

my step-sons are

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 2,1 (Subtype 2,6)

Lisa Mentor
Lisa
Posted

I like Gloria Vanderbilt...oh genes. Don't know mine, a biopsy sealed it for me. ;)

Teacher1958 Apprentice
Teacher1958
Posted
Ok I have been intrigued with the celiac and gluten genes. So i was hoping everyone can post their genes.

paula

Oh my gosh! Do you guys actually know what all that means? If I have this test done eventually, will someone interpret it for me? Yikes!

mftnchn Explorer
mftnchn
Posted

Here's mine:

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0201

Serologic equivalent: HLA-DQ 2,2 (Subtype 2,2)

dally099 Contributor
dally099
Posted
Here's mine:

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0201

Serologic equivalent: HLA-DQ 2,2 (Subtype 2,2)

heres mine: dont ask me what they mean though,

HLA-DQB1 Molecular analysis, allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0502

Serologic equivalent: HLA-DQ 3,1 (subtype 8,5)

hey if anyone knows what the heck this all means would love to here it. thanks nadine

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


GeoffCJ Enthusiast
GeoffCJ
Posted

Today - Old Navy.

Normally - Levis

But I'm working on switching the wardrobe to organic cotton.

I don't know my Gene's despite paying for the test from Enterolab. I'd have to look. I was diagnosed both by biopsy, diet, and Enterolab. Having had so many wrong diagnosis-es over the years, there was really no way I was going to let any one test change my life. All three pretty much confirmed each other, and that sealed the deal.

Geoff

dlp252 Apprentice
dlp252
Posted

Mine are in my signature because I can never remember what they are.

holiday16 Enthusiast
holiday16
Posted

I never had the gene test done so I only know from deduction what mine are since my parents had theirs done. My mother's was:

HLA-DQB1 Molecular analysis, Allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0501

Serologic equivalent: HLA-DQ 3,1 (Subtype 8,5)

and my dad's was:

Serologic equivalent: HLA-DQ 3,3 (Subtype 7,7)

Since my dad has a double gene I know I have the 7 and then either an 8 or 5 from my mother. Interestingly enough even though it's my mother that has the celiac gene it was my dad that tested positive for gluten intolerance. My brother is postive as well and he has the 7 and 8 genes.

burdee Enthusiast
burdee
Posted

Here's my Enterolab gene test results. Everyone who tests with Elab will get an explanation of their genetic (and other test) results. I also posted the interpretation included in my Elab gene test results:

Gene Test for Gluten Sensitivity

Molecular Analysis: HLA-DQB1*0602, 0302

Serologic equivalent: HLA-DQ 1,3 (subtype 6,8)

HLA gene analysis reveals that you have a copy of one of the main genes that predisposes to gluten sensitivity and celiac sprue, HLA-DQ3, subtype 8 (HLA-DQ8). This genotype also can predispose to microscopic colitis and other autoimmune syndromes.

BURDEE

happygirl Collaborator
happygirl
Posted

HLA DQ8

Nantzie Collaborator
Nantzie
Posted

Mine:

HLA-DQB1*0602, 0609

Daughter's:

HLA-DQB1*0609, 0301

Son's:

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

..........................

Husband hasn't had his done, but he obviously has at least one copy of HLA-DQB1 Molecular analysis, Allele 1 0301 .

Nancy

confused Community Regular
confused
Posted
  • Author

Thanks everyone that posted. I had some thoughts going threw my head yesterday and wanted to compare gene types, and see who had genes like mine. Plus i want to do some research on gene types sometime in the near future. I have to much going on right now to think straight, but it is on my 2 to list lol

paula

jerseyangel Proficient
jerseyangel
Posted
Mine are in my signature because I can never remember what they are.

:D Mine, too!

happygirl Collaborator
happygirl
Posted
heres mine: dont ask me what they mean though,

HLA-DQB1 Molecular analysis, allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0502

Serologic equivalent: HLA-DQ 3,1 (subtype 8,5)

hey if anyone knows what the heck this all means would love to here it. thanks nadine

Your HLA DQ 3 subtype 8 is what is referred to as HLA DQ 8, which is a Celiac gene.

from wikipedia:

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

DQ7 = DQB1*0301 (or very similar alleles)

DQ8 = DQB1*0302 (or very similar alleles)

DQ9 = DQB1*0303 (or very similar alleles)

pedro Explorer
pedro
Posted

Hi

Please below my name. You will find them.

confused Community Regular
confused
Posted
  • Author
Your HLA DQ 3 subtype 8 is what is referred to as HLA DQ 8, which is a Celiac gene.

from wikipedia:

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

DQ7 = DQB1*0301 (or very similar alleles)

DQ8 = DQB1*0302 (or very similar alleles)

DQ9 = DQB1*0303 (or very similar alleles)

See this is one of the things that i am really interested in. I am dqb1 0301, which i think is very close to dqb1 0302. I am not sure how close they are but would really like to find out.

paula

happygirl Collaborator
happygirl
Posted
Here are mine

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

close doesn't mean the same though.

the entire explanation, from wikipedia:

Note on DQ Serotype Names in Relationship with Allele Names

DQ serotypes are usually a recognition of Beta chain isoform groups For example, DQ2 = alleles that start with DQB1*02 (*0201, *0202, and *0203).

DQ2 is encoded by alleles that start with DQB1*02

DQ4 is encoded by alleles that start with DQB1*04

There are two exceptions worth noting:

DQ1 is 'split' into DQ5 and DQ6, in this case the DQB1 alleles start with

-DQ5 encoded by alleles that start with DQB1*05

-DQ6 encoded by alleles that start with DQB1*06

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

-DQ7 = DQB1*0301 (or very similar alleles)

-DQ8 = DQB1*0302 (or very similar alleles)

-DQ9 = DQB1*0303 (or very similar alleles)

You are DQ6 and DQ7.

SUZ42 Explorer
SUZ42
Posted

DQ 3 (7)

DQ 3 (8)

confused Community Regular
confused
Posted
  • Author
close doesn't mean the same though.

the entire explanation, from wikipedia:

Note on DQ Serotype Names in Relationship with Allele Names

DQ serotypes are usually a recognition of Beta chain isoform groups For example, DQ2 = alleles that start with DQB1*02 (*0201, *0202, and *0203).

DQ2 is encoded by alleles that start with DQB1*02

DQ4 is encoded by alleles that start with DQB1*04

There are two exceptions worth noting:

DQ1 is 'split' into DQ5 and DQ6, in this case the DQB1 alleles start with

-DQ5 encoded by alleles that start with DQB1*05

-DQ6 encoded by alleles that start with DQB1*06

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

-DQ7 = DQB1*0301 (or very similar alleles)

-DQ8 = DQB1*0302 (or very similar alleles)

-DQ9 = DQB1*0303 (or very similar alleles)

You are DQ6 and DQ7.

thank you for posting that.

Does anyone know of an good book that explains all this., or is it bestjust to do all my seaching online

paula

Nancym Enthusiast
Nancym
Posted

HLA-DQB1 Molecular analysis, Allele 1 0302 (DQ8 -- Celiac)

HLA-DQB1 Molecular analysis, Allele 1 0501 (DQ1 -- Gluten Sensitivity Dr. Hadjivasilliou finds this one in brain related gluten issues)

AndreaB Contributor
AndreaB
Posted

Mine: HLA-DQ 2,3 (subtype 2,7) or DQ2 and DQ7

Husband: HLA-DQ 2,3 (subtype 2,8) or DQ2 and DQ8

Daughter:HLA-DQ 3,3 (subtype 8,7) or DQ8 and DQ7

Son: HLA-DQ 2,2 (subtype 2,2) or Double DQ2

Son: Haven't gene tested yet but DQ2, 7 or 8 are the only possibilities.

happygirl Collaborator
happygirl
Posted
thank you for posting that.

Does anyone know of an good book that explains all this., or is it bestjust to do all my seaching online

paula

Paula,

You are welcome :).

I've found the best info online. go to wikipedia, and search for hla dq2, and click on the first link...I think its a great comprehensive overview of the hla dq genes of interest to us.

confused Community Regular
confused
Posted
  • Author

Thanks for that info. Yesterday i just kept typing in the difference between 7 and 8, i didnt hink to type just in 7 lol. I am going to try and do some more research today. I even emailed enterolab to see what they will tell me, I am sure i wont hear from them til next week tho.

paula

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. Colleen H
      - Colleen H replied to Colleen H's topic in Coping with Celiac Disease
      2

      Gluten related ??

      Thank you so much for your response Yes it seems as though things get very painful as time goes on. I'm not eating gluten as far as I know. However, I'm not sure of cross contamination. My system seems to weaken to hidden spices and other possibilities. ??? if cross contamination is possible...I am in a super sensitive mode of celiac disease...
    2. Jmartes71
      - Jmartes71 replied to Jmartes71's topic in Coping with Celiac Disease
      4

      My only proof

      EXACTLY! I was asked yesterday on my LAST video call with Standford and I stated exactly yes absolutely this is why I need the name! One, get proper care, two, not get worse.Im falling apart, stressed out, in pain and just opened email from Stanford stating I was rude ect.I want that video reviewed by higher ups and see if that women still has a job or not...
    3. AlwaysLearning
      - AlwaysLearning replied to Jmartes71's topic in Coping with Celiac Disease
      4

      My only proof

      We feel your pain. It took me 20+ years of regularly going to doctors desperate for answers only to be told there was nothing wrong with me … when I was 20 pounds underweight, suffering from severe nutritional deficiencies, and in a great deal of pain. I had to figure it out for myself. If you're in the U.S., not having an official diagnosis does m...
    4. AlwaysLearning
      - AlwaysLearning replied to Colleen H's topic in Coping with Celiac Disease
      2

      Gluten related ??

      If you're just starting out in being gluten free, I would expect it to take months before you learned enough about hidden sources of gluten before you stopped making major mistakes. Ice cream? Not safe unless they say it is gluten free. Spaghetti sauce? Not safe unless is says gluten-free. Natural ingredients? Who knows what's in there. You pretty much...
    5. Scott Adams
      0

      Häagen-Dazs Chocolate Dark Chocolate Mini Bars Recall Due to Undeclared Wheat and Gluten

  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      132,076
    • Most Online (within 30 mins)
      7,748
    Deb baker
    Newest Member
    Deb baker
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Colleen H
      Gluten related ??

      By Colleen H · Posted

      Thank you so much for your response  Yes it seems as though things get very painful as time goes on.  I'm not eating gluten as far as I know.  However, I'm not sure of cross contamination.  My system seems to weaken to hidden spices and other possibilities. ???  if cross contamination is possible...I am in a super sensitive mode of celiac disease.. Neuropathy from head to toes
    • Jmartes71
      My only proof

      By Jmartes71 · Posted

      EXACTLY! I was asked yesterday on my LAST video call with Standford and I stated exactly yes absolutely this is why I need the name! One, get proper care, two, not get worse.Im falling apart, stressed out, in pain and just opened email from Stanford stating I was rude ect.I want that video reviewed by higher ups and see if that women still has a job or not.Im saying this because I've been medically screwed and asking for help because bills don't pay itself. This could be malpratice siit but im not good at finding lawyers
    • AlwaysLearning
      My only proof

      By AlwaysLearning · Posted

      We feel your pain. It took me 20+ years of regularly going to doctors desperate for answers only to be told there was nothing wrong with me … when I was 20 pounds underweight, suffering from severe nutritional deficiencies, and in a great deal of pain. I had to figure it out for myself. If you're in the U.S., not having an official diagnosis does mean you can't claim a tax deduction for the extra expense of gluten-free foods. But it can also be a good thing. Pre-existing conditions might be a reason why a health insurance company might reject your application or charge you more money. No official diagnosis means you don't have a pre-existing condition. I really hope you don't live in the U.S. and don't have these challenges. Do you need an official diagnosis for a specific reason? Else, I wouldn't worry about it. As long as you're diligent in remaining gluten free, your body should be healing as much as possible so there isn't much else you could do anyway. And there are plenty of us out here who never got that official diagnosis because we couldn't eat enough gluten to get tested. Now that the IL-2 test is available, I suppose I could take it, but I don't feel the need. Someone else not believing me really isn't my problem as long as I can stay in control of my own food.
    • AlwaysLearning
      Gluten related ??

      By AlwaysLearning · Posted

      If you're just starting out in being gluten free, I would expect it to take months before you learned enough about hidden sources of gluten before you stopped making major mistakes. Ice cream? Not safe unless they say it is gluten free. Spaghetti sauce? Not safe unless is says gluten-free. Natural ingredients? Who knows what's in there. You pretty much need to cook with whole ingredients yourself to avoid it completely. Most gluten-free products should be safe, but while you're in the hypersensitive phase right after going gluten free, you may notice that when something like a microwave meal seems to not be gluten-free … then you find out that it is produced in a shared facility where it can become contaminated. My reactions were much-more severe after going gluten free. The analogy that I use is that you had a whole army of soldiers waiting for some gluten to attack, and now that you took away their target, when the stragglers from the gluten army accidentally wander onto the battlefield, you still have your entire army going out and attacking them. Expect it to take two years before all of the training facilities that were producing your soldiers have fallen into disrepair and are no longer producing soldiers. But that is two years after you stop accidentally glutening yourself. Every time you do eat gluten, another training facility can be built and more soldiers will be waiting to attack. Good luck figuring things out.   
    • Russ H
      KAN-101 Treatment for Coeliac Disease

      By Russ H · Posted

      This treatment looks promising. Its aim is to provoke immune tolerance of gluten, possibly curing the disease. It passed the phase 2 trial with flying colours, and I came across a post on Reddit by one of the study volunteers. Apparently, the results were good enough that the company is applying for fast track approval.  Anokion Announces Positive Symptom Data from its Phase 2 Trial Evaluating KAN-101 for the Treatment of Celiac Disease https://www.reddit.com/r/Celiac/comments/1krx2wh/kan_101_trial_put_on_hold/
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.