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Celiac Disease Pre-Diagnosis, Testing & Symptoms
If you haven't yet been diagnosed this is the place you can discuss your symptoms and any test results that may indicate that you might have the disease.
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Recent Activity
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- knitty kitty replied to Zuma888's topic in Related Issues & Disorders11Burning sensation when I wake up
@Healthforme, No prescription needed for thiamine hydrochloride, Benfotiamine, and TTFD (Tetrahydrofurfuryl Disulfide). They are available over the counter. Thiamine Mononitrate is not recommended because the body doesn't absorb or utilize it well.- 1
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- knitty kitty replied to Zuma888's topic in Related Issues & Disorders11
Burning sensation when I wake up
@Zuma888, I'm so happy you're feeling better! Thanks for letting us know of your improvement!- 1
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- RMJ replied to Kirita's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms2Help with genetic testing
HLA-DQ2 is NOT a continuum 2.01 to 2.99, but I don’t understand HLA genetics well enough to explain it further. It is not just one gene that is either this or that. -
- trents replied to Kirita's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms2Help with genetic testing
Okay, I'm taking a guess here. We are used to hearing in layman terms that having either the HLA-DQ2 or the HLA-DQ8 gene, either heterozygous or homozygous, presents the possibility of developing active celiac disease. So, I'm guessing that the HLA-DQ2 gene is actually a range of variants (2.01-2.99) with HLA-DQ 2.5 being in the centerpiece of the range... -
- Kirita posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms2Help with genetic testing
I received the results that my child has the genes for celiac disease (she is still undergoing testing and it has been complicated). Can someone explain if this is homozygous HLA DQ 2.5 or not? The interpretation just says permissive for celiac disease. Thank you! DQ Alpha 1 05:01, 5 DQ Beta 1 02:01, 02:01 DQ serologic...
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By knitty kitty · Posted
@Healthforme, No prescription needed for thiamine hydrochloride, Benfotiamine, and TTFD (Tetrahydrofurfuryl Disulfide). They are available over the counter. Thiamine Mononitrate is not recommended because the body doesn't absorb or utilize it well. -
By knitty kitty · Posted
@Zuma888, I'm so happy you're feeling better! Thanks for letting us know of your improvement! -
HLA-DQ2 is NOT a continuum 2.01 to 2.99, but I don’t understand HLA genetics well enough to explain it further. It is not just one gene that is either this or that.
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Okay, I'm taking a guess here. We are used to hearing in layman terms that having either the HLA-DQ2 or the HLA-DQ8 gene, either heterozygous or homozygous, presents the possibility of developing active celiac disease. So, I'm guessing that the HLA-DQ2 gene is actually a range of variants (2.01-2.99) with HLA-DQ 2.5 being in the centerpiece of the range. I'm also guessing that "permissive" is equivalent to "possessing the possibility" to develop active celiac disease and does not address the issue of hetero vs. homozygus per se. But the fact that 2.01,2.01 is a couplet may indicated homozygousity? All wild guesses.
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I received the results that my child has the genes for celiac disease (she is still undergoing testing and it has been complicated). Can someone explain if this is homozygous HLA DQ 2.5 or not? The interpretation just says permissive for celiac disease. Thank you! DQ Alpha 1 05:01, 5 DQ Beta 1 02:01, 02:01 DQ serologic equivalent 2,2
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