Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Super Over-Reactions To Novacaine, Etc.

IrishHeart

By IrishHeart
in Super Sensitive People

Recommended Posts

IrishHeart Veteran
IrishHeart
Posted

Maybe you other super sensitives know why I react so strongly to even the smallest doses of medications, and to novacaine at the dentist, even the eye drops at the eye doctor yesterday. (They just confirmed to me that it is rare for someone's pupils to remain dilated and light- sensitive longer than 24 hours and for my face to be flushed red hot, plus I feel agitated and nauseous.They said some people lack a certain protein which affects how one responds to these drugs? I don't know--all I Know is my vision is still blurry. :blink: ) These kinds of things affect me for days--I feel sick and out of it. Geesh!

I know it's not gluten doing it, but I am just wondering if anyone else has these "heightened" responses--almost like an allergy-- to meds that usually wear off shortly in other people?

Thanks, guys ;) .

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


GlutenFreeManna Rising Star
GlutenFreeManna
Posted

Oh my YES! I take one Benedryl and I am knocked out. I can't keep my eyes open. If I take two Bendryl I will sleep for at least 12 hours and be really groggy/strugglign to wake up for the next 48 hours. I can't take strong pain killers (Opiate-based) without really severe reactions. The only things I don't really have trouble with is Ibuprofen and Pepto Bismol. I would love to know why and if this is at all related to gluten.

IrishHeart Veteran
IrishHeart
Posted
  • Author

Oh my YES! I take one Benedryl and I am knocked out. I can't keep my eyes open. If I take two Bendryl I will sleep for at least 12 hours and be really groggy/strugglign to wake up for the next 48 hours. I can't take strong pain killers (Opiate-based) without really severe reactions. The only things I don't really have trouble with is Ibuprofen and Pepto Bismol. I would love to know why and if this is at all related to gluten.

That is weird, because when I take opiods--I get AGITATED instead of knocked out :blink: Sleep meds, pain meds??---might as well give me shots of adrenaline.

If I take a xanax--offered to me for sleep?--or flexeril for muscle pain---I am doped up for a few days...even a little tiny bit does me in. So, I don't take anything!

Benadryl--I lie awake with heart palps and raciness....almost like I do with gluten---which BTW...I call the "gluten willies" :lol:

One doctor suggested it is because we are not absorbing medications properly because of our guts...makes sense? I know that in years past, I had no trouble with meds, etc..,.,just since I got sick.

GlutenFreeManna Rising Star
GlutenFreeManna
Posted

That is weird, because when I take opiods--I get AGITATED instead of knocked out :blink: Sleep meds, pain meds??---might as well give me shots of adrenaline.

If I take a xanax--offered to me for sleep?--or flexeril for muscle pain---I am doped up for a few days...even a little tiny bit does me in. So, I don't take anything!

Benadryl--I lie awake with heart palps and raciness....almost like I do with gluten---which BTW...I call the "gluten willies" :lol:

One doctor suggested it is because we are not absorbing medications properly because of our guts...makes sense? I know that in years past, I had no trouble with meds, etc..,.,just since I got sick.

I have that reaction to Sudafed--the heart racing and wide-awake, feelign like I could run a marathon or liek I just ingested a large amount of caffiene. My chest hurts for days afterward. I wonder if we could be reacting to the dyes in some meds?

I also get really, really emotional from pain meds that don't knock me out. Like, my husband could tell me that we are out of toilet paper and I would break down crying as if my best friend just died. And I don't know why I am crying over it, just that I can't stop. I had a concussion a few years ago and this was my reaction to taking one vicodin. Crying jags for days over little things that didn't matter to me. I thought I was losing my mind.

lovegrov Collaborator
lovegrov
Posted

There are folks who do not have celiac who have similar problems. Doubt celiac has anything to do with it.

richard

Poppi Enthusiast
Poppi
Posted

I'm like that too. My heart races like crazy when I get a novocaine shot at the dentist. He told me there is adrenaline mixed into the medication but that most people don't feel it like I do. Last time he was numbing me up for a root canal I thought my heart was going to stop, even the dentist got worried for a minute of two.

cahill Collaborator
cahill
Posted

My GI doc recently diagnosed me with Gilbert-Meulengracht syndrome,

one of the complications of Gilbert's is that the liver is unable to detoxify the body of certain drugs leading to ,,among other things,,a hypersensitivity to those drugs .

My daughter is totally convinced that my celiac's is connected to my Gilbert's . The origin of Gilberts is a flaw(?) in ones DNA,, makes me wonder :huh:

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


IrishHeart Veteran
IrishHeart
Posted
  • Author

My GI doc recently diagnosed me with Gilbert-Meulengracht syndrome,

one of the complications of Gilbert's is that the liver is unable to detoxify the body of certain drugs leading to ,,among other things,,a hypersensitivity to those drugs .

My daughter is totally convinced that my celiac's is connected to my Gilbert's . The origin of Gilberts is a flaw(?) in ones DNA,, makes me wonder :huh:

That's what my doctor suggested --that the liver might be having trouble filtering drugs. I was pretty jaundiced for a while there. Not anymore. Thanks for your thoughts! Whatever the case, it sure makes me "racy" :rolleyes: My dentist feels bad whenever he has to work on me :lol:

IrishHeart Veteran
IrishHeart
Posted
  • Author

I'm like that too. My heart races like crazy when I get a novocaine shot at the dentist. He told me there is adrenaline mixed into the medication but that most people don't feel it like I do. Last time he was numbing me up for a root canal I thought my heart was going to stop, even the dentist got worried for a minute of two.

me, too--and I got cold and started to tremble..they put a blanket on me--I felt like such a silly .... :rolleyes:

cahill Collaborator
cahill
Posted

That's what my doctor suggested --that the liver might be having trouble filtering drugs. I was pretty jaundiced for a while there. Not anymore. Thanks for your thoughts! Whatever the case, it sure makes me "racy" :rolleyes: My dentist feels bad whenever he has to work on me :lol:

I knew I was pretty jaundiced when my 6 year old granddaughter said to me " gram you look like a banana :lol:

I try to avoid any drugs ,even OTC drugs, if at all possible

IrishHeart Veteran
IrishHeart
Posted
  • Author

I knew I was pretty jaundiced when my 6 year old granddaughter said to me " gram you look like a banana :lol:

I try to avoid any drugs ,even OTC drugs, if at all possible

banana huh? :) -- I was more "golden beige"... :blink:

me too...I suffer with chronic pain rather than take anything...geesh!

domesticactivist Collaborator
domesticactivist
Posted

I don't have celiac but I'm also very sensitive to medications and over the years have really minimized their use. It seems like if there's a rare side effect, I'll get it, and half the time medications don't have the intended effect on me. My dad is the same way.

I have a friend with grave's disease who also reacts very strongly to novacaine, btw.

IrishHeart Veteran
IrishHeart
Posted
  • Author

I don't have celiac but I'm also very sensitive to medications and over the years have really minimized their use. It seems like if there's a rare side effect, I'll get it, and half the time medications don't have the intended effect on me. My dad is the same way.

I have a friend with grave's disease who also reacts very strongly to novacaine, btw.

Thanks for your thoughts. Yes, my Mom shares my "sensitivity" as well. You should have seen me on morphine post- hysterectomy--yikes!! Not good. :blink:

I am like you--if it has a "rare" side effect--I'm sure to have it occur!

I am sitting here with sunglasses on having had my pupils dilated YESTERDAY for an exam...my vision is still blurry and my irises are practically non-existent. Doctor says it is very rare, well, maybe...but it happened, nonetheless. B) Lucky me :P

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. Wheatwacked
      - Wheatwacked replied to bold-95's topic in Introduce Yourself / Share Stuff
      2

      I hate to cook!

      In 70-year-olds, DHEA (Dehydroepiandrosterone) levels are significantly lower than in young adults, typically around 20% of youthful levels, according to the National Institutes of Health (NIH) | (.gov). This decline is a natural part of aging, with DHEA production decreasing from its peak in the third decade of life. While some studies suggest potential...
    2. Wheatwacked
      - Wheatwacked replied to bold-95's topic in Introduce Yourself / Share Stuff
      2

      I hate to cook!

      Welcome @bold-95. That's a tough situation. Understanding DHEA Deficiency in Menopausal Women A major cause of hypothyroid is iodine deficiency. In the 60's bread had 90 mcg, milk 100 mcg per cup and we used iodized table salt. A sandwich and glass of milk supplied 300 mcg, Now in the US bread does not use iodine as dough condition...
    3. Wheatwacked
      - Wheatwacked replied to Mrs Wolfe's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      6

      Cartilage and rib pain.

      For minor aches and pains, my go to is Original Alka-Seltzer. Aspirin and bicarbonate. It is dissoved in water before you swallow it so no tablets to aggravate the stomach wall. The bicarbonate buffers the stomach acid for upset stomach. Willow bark contains a chemical called salicin, which is similar to aspirin. It has pain and fever reducing effects...
    4. knitty kitty
      - knitty kitty replied to Mrs Wolfe's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      6

      Cartilage and rib pain.

      @bold-95, welcome to the forum. Rib pain can be caused by Chondritis, an inflammation of the cartilage in the ribcage or breastbone. Vitamin D deficiency causes this condition and Osteopenia. Celiac disease damages the lining of the small intestine, making absorption of nutrients like vitamins difficult. Nutritional deficiencies result. Diseases...
    5. bold-95
      - bold-95 replied to Diana Swales's topic in Introduce Yourself / Share Stuff
      4

      Recently qualified Nutritionist looking for support

      Diana, I replied “ready,” but I’m brand new to the site and don’t know if I replied via the correct place. I would like to participate.
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      130,397
    • Most Online (within 30 mins)
      7,748
    yamipe8328
    Newest Member
    yamipe8328
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Wheatwacked
      I hate to cook!

      By Wheatwacked · Posted

      In 70-year-olds, DHEA (Dehydroepiandrosterone) levels are significantly lower than in young adults, typically around 20% of youthful levels, according to the National Institutes of Health (NIH) | (.gov). This decline is a natural part of aging, with DHEA production decreasing from its peak in the third decade of life. While some studies suggest potential benefits of DHEA replacement in older adults, particularly in women, results are not consistently positive across all studies. 
    • Wheatwacked
      I hate to cook!

      By Wheatwacked · Posted

      Welcome @bold-95.   That's a tough situation.   Understanding DHEA Deficiency in Menopausal Women A major cause of hypothyroid is iodine deficiency.  In the 60's bread had 90 mcg, milk 100 mcg per cup and we used iodized table salt.  A sandwich and glass of milk supplied 300 mcg,  Now in the US bread does not use iodine as dough condition, milk has a bad name and table salt is avoided.  Net reduction from 1970 to 1984 of 50% of iodine intake.   Urinary iodine levels (mg/dL) in the United States, 6-74 years of age NHANES I, 1971-74 Median 32.00 2NHANES III, 1988-91 Median 14.5 NHANES 2000 Median 16.1 There has been a trend for increased prescribing of levothyroxine (LT4) in the United States.  LT4 was the tenth and seventh most commonly prescribed drug based on the number of prescriptions in 2005 and 2006, respectively. From 2008 to 2011 the number of LT4 prescriptions rose from 99 million to 105 million, with LT4 being the second most prescribed medication.1 From 2012 to 2016 the number of annual LT4 prescriptions increased steadily from 112 million to 123 million, with LT4 being the most prescribed medication.2,3 During 2017 and 2018 LT4 was the third most prescribed medication, with 98 million Levothyroxine prescriptions trends may indicate a downtrend in prescribing. DHEA and hypothyroidism are linked, with some evidence suggesting that low DHEA levels may be associated with hypothyroidism.
    • Wheatwacked
      Cartilage and rib pain.

      By Wheatwacked · Posted

      For minor aches and pains, my go to is Original Alka-Seltzer.  Aspirin and bicarbonate.  It is dissoved in water before you swallow it so no tablets to aggravate the stomach wall.  The bicarbonate buffers the stomach acid for upset stomach. Willow bark contains a chemical called salicin, which is similar to aspirin. It has pain and fever reducing effects in the body. The last time I took Advil for serious pain it spiked my BP to 190. Some blood pressure medications have been linked to rib pain or musculoskeletal pain as a side effect.  I had to stop Atnenolol because it had me bent over like a 90 year old with a walker.  Another med prescribe by my doctor left my knees unstable.  Currently, Losartan has weakened my back and thighs.  Can't walk to my mailbox at the street and back without having to rest my legs.  Upper body is however increasing muscle mass.  No one believes me though; think I'm malingering.  Those blood pressure meds also had no effect on my BP, but doctor wants me to continue on (man up, its good for you, with the Losartan + clonidine.  What has been working is Clonidine.  It has lowered my BP. but it is considered third tier BP med.  No side effects and it lowers my BP from 160+ to between 115 and 139.  
    • knitty kitty
      Cartilage and rib pain.

      By knitty kitty · Posted

      @bold-95, welcome to the forum. Rib pain can be caused by Chondritis, an inflammation of the cartilage in the ribcage or breastbone.  Vitamin D deficiency causes this condition and Osteopenia. Celiac disease damages the lining of the small intestine, making absorption of nutrients like vitamins difficult.  Nutritional deficiencies result.  Diseases can be caused by not having enough of certain vitamins and minerals. Vitamins are chemical compounds that our bodies cannot make, so we must get them from food or supplements.  Vitamins are crucial to our bodies functioning properly.  Eating a nutritionally dense diet is important, but to correct nutritional deficiencies, supplemental vitamins are needed.   Over the counter pain relievers like NSAIDs and PPIs can cause additional inflammation and damage to the small intestine.  OTC pain relievers worked for me but they hurt my digestive system worse.  Yes, Cobalamine Vitamin B12, Pyridoxine B 6, and Thiamine B 1 have an analgesic effect when taken together.   I'm leaving links below so you can see for yourself.   Analgesic and analgesia-potentiating action of B vitamins.     https://pubmed.ncbi.nlm.nih.gov/12799982/#:~:text=Disregarding pain resulting from vitamin,three are given in combination.   Mechanisms of action of vitamin B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) in pain: a narrative review https://pubmed.ncbi.nlm.nih.gov/35156556/   B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin https://pubmed.ncbi.nlm.nih.gov/31490017/   Role of B vitamins, thiamine, pyridoxine, and cyanocobalamin in back pain and other musculoskeletal conditions: a narrative review https://pubmed.ncbi.nlm.nih.gov/33865694/   The Combination of Neurotropic Vitamins B1, B6, and B12 Enhances Neural Cell Maturation and Connectivity Superior to Single B Vitamins https://pmc.ncbi.nlm.nih.gov/articles/PMC11987730/  
    • bold-95
      Recently qualified Nutritionist looking for support

      By bold-95 · Posted

      Diana, I replied “ready,” but I’m brand new to the site and don’t know if I replied via the correct place.  I would like to participate.
×
×
  • Create New...