Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Recurrent Miscarriage And Celiac?

Rayrab

Recommended Posts

Rayrab Newbie
Rayrab
Posted

After multiple miscarriages, despite the birth of a healthy son in2010, I started seeing a naturopath. She ordered a ton of blood work, including the panel for celiacs. I met with her yesterday and she believes I have it and wants me to do the genetic testing, which I have no problem with. However, I'm totally baffled that she would leap to celiacs given my results and my research here and elsewhere on the internet. 

 

I would really appreciate some feedback on these results: 

 

Deamidated Gliadin Abs, IGA <1 (negative 0-19)

Deamidated Glaiadin Abs, IgG 5 (negative0-19)

t-Transglutaminase  (tTG) IgA <2 (negative 0-3)

t-Transglutaminase (tTG) IgG <2 (negative 0 - 5)

Endomysial Antiody IgA  negative

Immunoglobulin A, Qn, Serum <15  Low (Negative 91- 414) 

 

From what I've read in my crash course in celiacs in the past 24 hours, the last one indicates that all the IGA tests are invalid. It seems most people recommend the tTG tests to rule out Celiacs, yes? So being that those are also negative, why would she assume celiacs? My understanding is that low IgA serum can be indicative of many immune deficiencies so why the leap to Celiac's? 

 

Also, I have been gluten-free for approximately 6 weeks, 5 when these labs were taken, merely because there is an association between gluten and recurrent miscarriage. From what I understand gluten would have to be out of my system for much longer than that to skew the tests in any way. Correct? 

 

There seems to be a lot of experience (unfortunately) here on these forums so I'm optimistic someone can calm my frantic mind before I can connect with my Naturopath again ;)  

 

Thanks in advance!! 

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


kareng Grand Master
kareng
Posted

Looks like she did every possible blood test and they are all negative. Even tho your IGA is low, they did the IGG version, too. Cleiac can cause miscarriages. Perhaps you should consult an MD OB/GYN?

nvsmom Community Regular
nvsmom
Posted

You might want to consider an endoscopic biopsy if you think celiac disease is an answer (based on symptoms or familial history). Some people will have negative blood work and a positive biopsy - it's not common but it's not rare either.

 

Some people's antibody levels can fall to normal within weeks, for some it takes much longer. The problem is that there is no way of knowing which group you fall into except to resume eating gluten for about 6 weeks and then retest (the IgG tests that is).

 

Do you have other symptoms of celiac disease besides MC's (so sorry to hear about that) and low IgA that made your NP suspect celiac disease?  Are you feeling better gluten-free?

emaegf Newbie
emaegf
Posted

Blood results as well as endoscope testing will Not be reliable since you are already gluten free.  More tham likely you may have false negatives do to being on a gluten free diet for the five weeks prior to testing.

 

The blood tests look for the antibodies your body produces in response to the gluten you eat so when you remove the gluten the body has nothing to form antibodies against so there none for the blood tests to read.  Yes you could still have villi damage that can only be seen by doing a endoscope and taking samples of the intestines. But depending on how badly the damage internally was there also may come out negative do to the damage healing which starts within 24 hours of total removal of gluten from the diet.

 

 

So your best option is the genetic test unless you're willing to go back to eating gluten for 6-12 weeks and then having the blood work and endoscope done. But still if you do have a gene linked to Celiac you may not actually have active Celiac so also do go to a reproductive specialist if you aren't already.

IrishHeart Veteran
IrishHeart
Posted

Your celiac test results could well be invalid because you were off gluten. Hard to say.

 

If I were my 30-something year old self again (after having had multiple miscarriages and never carrying to term), I'd go to a reproductive endocrinologist. I know a whole lot more now than I did back then and one is:  Fertility doctors may not get to the root of the problem.

and the other is: Naturopaths have their value, but for this particular health issue, you need a specialist,  IMHO.

 

Could it be a gluten-related issue--and not necessarily celiac? absolutely. Plenty of medical lit that discusses this relationship.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,543
    • Most Online (within 30 mins)
      7,748
    yfuvhg
    Newest Member
    yfuvhg
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Beverage
      Diagnosed celiac for 1-2 months ago and everything makes me bloated.

      By Beverage · Posted

      I had a very rough month after diagnosis. No exaggeration, lost so much inflammatory weight, I looked like a bag of bones, underneath i had been literally starving to death. I did start feeling noticeably better after a month of very strict control of my kitchen and home. What are you eating for breakfast and lunch? I ignored my doc and ate oats, yes they were gluten free, but some brands are at the higher end of gluten free. Lots of celics can eat Bob's Red Mill gluten-free oats, but not me. I can now eat them, but they have to be grown and processed according to the "purity protocol" methods. I mail order them, Montana Gluten-Free brand. A food and symptoms and activities log can be helpful in tracking down issues. You might be totally aware, but I have to mention about the risk of airborne gluten. As the doc that diagnosed me warned . . Remember eyes, ears, nose, and mouth all lead to your stomach and intestines.  Are you getting any cross contamination? Airborne gluten? Any pets eating gluten (they eat it, lick themselves, you pet them...)? Any house remodeling? We live in an older home, always fixing something. I've gotten glutened from the dust from cutting into plaster walls, possibly also plywood (glues). The suggestions by many here on vitamin supplements also really helped me. I had some lingering allergies and asthma, which are now 99% gone. I was taking Albuterol inhaler every hour just to breathe, but thiamine in form of benfotiamine kicked that down to 1-2 times a day within a few days of starting it. Also, since cutting out inflammatory seed oils (canola, sunflower, grapeseed, etc) and cooking with real olive oil, avocado oil, ghee, and coconut oil, I have noticed even greater improvement overall and haven't used the inhaler in months! It takes time to weed out everything in your life that contains gluten, and it takes awhile to heal and rebuild your health. At first it's mentally exhausting, overwhelming, even obsessive, but it gets better and second nature.
    • Jsingh
      Protein or fat?

      By Jsingh · Posted

      Hi,  I care for my seven year old daughter with Celiac. After watching her for months, I have figured out that she has problem with two kinds of fats- animal fat and cooking oils. It basically makes her intestine sore enough that she feels spasms when she is upset. It only happens on days when she has eaten more fat than her usual every day diet. (Her usual diet has chia seeds, flaxseeds, and avocado/ pumpkin seeds for fat and an occasional chicken breast.) I stopped using cooking oils last year, and when I reintroduced eggs and dairy, both of which I had held off for a few months thinking it was an issue of the protein like some Celiac patients habe mentioned to be the case, she has reacted in the same fashion as she does with excess fats. So now I wonder if her reaction to dairy and eggs is not really because of protein but fat.   I don't really have a question, just wondering if anyone finds this familiar and if it gets better with time.  Thank you. 
    • Chanda Richard
      High Cost of Gluten-Free Foods

      By Chanda Richard · Posted

      Hello, My name is Chanda and you are not the only one that gose through the same things. I have found that what's easiest for me is finding a few meals each week that last. I have such severe reactions to gluten that it shuts my entire body down. I struggle everyday with i can't eat enough it feels like, when I eat more I lose more weight. Make sure that you look at medication, vitamins and shampoo and conditioner also. They have different things that are less expensive at Walmart. 
    • petitojou
      Frequent nausea after gluten-free diet

      By petitojou · Posted

      Thank you so much! I saw some tips around the forum to make a food diary and now that I know that the community also struggles with corn, egg and soy, the puzzle pieces came together! Just yesterday I tried eating eggs and yes, he’s guilty and charged. Those there are my 3 combo nausea troublemakers. I’m going to adjust my diet ☺️ Also thank you for the information about MCAS! I’m from South America and little it’s talked about it in here. It’s honestly such a game changer now for treatment and recovery. I know I’m free from SIBO and Candida since I’ve been tested for it, but I’m still going to make a endoscopy to test for H. Pylori and Eosinophilic esophagitis (EoE). Thank you again!! Have a blessed weekend 🤍
    • knitty kitty
      Unusual bright yellow but odourless discharge

      By knitty kitty · Posted

      Yes, I, too, have osteoporosis from years of malabsorption, too.  Thiamine and magnesium are what keep the calcium in place in the bones.  If one is low in magnesium, boron, selenium, zinc, copper, and other trace minerals, ones bone heath can suffer.  We need more than just calcium and Vitamin D for strong bones.  Riboflavin B 2, Folate B 9 and Pyridoxine B 6 also contribute to bone formation and strength.   Have you had your thyroid checked?  The thyroid is important to bone health as well.  The thyroid uses lots of thiamine, so a poorly functioning thyroid will affect bone heath.  
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.