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Can Everyone Post Their Genes


confused

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confused Community Regular

Ok I have been intrigued with the celiac and gluten genes. So i was hoping everyone can post their genes.

paula


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confused Community Regular

Here are mine

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

confused Community Regular

my step-sons are

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 2,1 (Subtype 2,6)

Lisa Mentor

I like Gloria Vanderbilt...oh genes. Don't know mine, a biopsy sealed it for me. ;)

Teacher1958 Apprentice
Ok I have been intrigued with the celiac and gluten genes. So i was hoping everyone can post their genes.

paula

Oh my gosh! Do you guys actually know what all that means? If I have this test done eventually, will someone interpret it for me? Yikes!

mftnchn Explorer

Here's mine:

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0201

Serologic equivalent: HLA-DQ 2,2 (Subtype 2,2)

dally099 Contributor
Here's mine:

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0201

Serologic equivalent: HLA-DQ 2,2 (Subtype 2,2)

heres mine: dont ask me what they mean though,

HLA-DQB1 Molecular analysis, allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0502

Serologic equivalent: HLA-DQ 3,1 (subtype 8,5)

hey if anyone knows what the heck this all means would love to here it. thanks nadine


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GeoffCJ Enthusiast

Today - Old Navy.

Normally - Levis

But I'm working on switching the wardrobe to organic cotton.

I don't know my Gene's despite paying for the test from Enterolab. I'd have to look. I was diagnosed both by biopsy, diet, and Enterolab. Having had so many wrong diagnosis-es over the years, there was really no way I was going to let any one test change my life. All three pretty much confirmed each other, and that sealed the deal.

Geoff

dlp252 Apprentice

Mine are in my signature because I can never remember what they are.

holiday16 Enthusiast

I never had the gene test done so I only know from deduction what mine are since my parents had theirs done. My mother's was:

HLA-DQB1 Molecular analysis, Allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0501

Serologic equivalent: HLA-DQ 3,1 (Subtype 8,5)

and my dad's was:

Serologic equivalent: HLA-DQ 3,3 (Subtype 7,7)

Since my dad has a double gene I know I have the 7 and then either an 8 or 5 from my mother. Interestingly enough even though it's my mother that has the celiac gene it was my dad that tested positive for gluten intolerance. My brother is postive as well and he has the 7 and 8 genes.

burdee Enthusiast

Here's my Enterolab gene test results. Everyone who tests with Elab will get an explanation of their genetic (and other test) results. I also posted the interpretation included in my Elab gene test results:

Gene Test for Gluten Sensitivity

Molecular Analysis: HLA-DQB1*0602, 0302

Serologic equivalent: HLA-DQ 1,3 (subtype 6,8)

HLA gene analysis reveals that you have a copy of one of the main genes that predisposes to gluten sensitivity and celiac sprue, HLA-DQ3, subtype 8 (HLA-DQ8). This genotype also can predispose to microscopic colitis and other autoimmune syndromes.

BURDEE

happygirl Collaborator

HLA DQ8

Nantzie Collaborator

Mine:

HLA-DQB1*0602, 0609

Daughter's:

HLA-DQB1*0609, 0301

Son's:

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

..........................

Husband hasn't had his done, but he obviously has at least one copy of HLA-DQB1 Molecular analysis, Allele 1 0301 .

Nancy

confused Community Regular

Thanks everyone that posted. I had some thoughts going threw my head yesterday and wanted to compare gene types, and see who had genes like mine. Plus i want to do some research on gene types sometime in the near future. I have to much going on right now to think straight, but it is on my 2 to list lol

paula

jerseyangel Proficient
Mine are in my signature because I can never remember what they are.

:D Mine, too!

happygirl Collaborator
heres mine: dont ask me what they mean though,

HLA-DQB1 Molecular analysis, allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0502

Serologic equivalent: HLA-DQ 3,1 (subtype 8,5)

hey if anyone knows what the heck this all means would love to here it. thanks nadine

Your HLA DQ 3 subtype 8 is what is referred to as HLA DQ 8, which is a Celiac gene.

from wikipedia:

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

DQ7 = DQB1*0301 (or very similar alleles)

DQ8 = DQB1*0302 (or very similar alleles)

DQ9 = DQB1*0303 (or very similar alleles)

pedro Explorer

Hi

Please below my name. You will find them.

confused Community Regular
Your HLA DQ 3 subtype 8 is what is referred to as HLA DQ 8, which is a Celiac gene.

from wikipedia:

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

DQ7 = DQB1*0301 (or very similar alleles)

DQ8 = DQB1*0302 (or very similar alleles)

DQ9 = DQB1*0303 (or very similar alleles)

See this is one of the things that i am really interested in. I am dqb1 0301, which i think is very close to dqb1 0302. I am not sure how close they are but would really like to find out.

paula

happygirl Collaborator
Here are mine

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

close doesn't mean the same though.

the entire explanation, from wikipedia:

Note on DQ Serotype Names in Relationship with Allele Names

DQ serotypes are usually a recognition of Beta chain isoform groups For example, DQ2 = alleles that start with DQB1*02 (*0201, *0202, and *0203).

DQ2 is encoded by alleles that start with DQB1*02

DQ4 is encoded by alleles that start with DQB1*04

There are two exceptions worth noting:

DQ1 is 'split' into DQ5 and DQ6, in this case the DQB1 alleles start with

-DQ5 encoded by alleles that start with DQB1*05

-DQ6 encoded by alleles that start with DQB1*06

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

-DQ7 = DQB1*0301 (or very similar alleles)

-DQ8 = DQB1*0302 (or very similar alleles)

-DQ9 = DQB1*0303 (or very similar alleles)

You are DQ6 and DQ7.

SUZ42 Explorer

DQ 3 (7)

DQ 3 (8)

confused Community Regular
close doesn't mean the same though.

the entire explanation, from wikipedia:

Note on DQ Serotype Names in Relationship with Allele Names

DQ serotypes are usually a recognition of Beta chain isoform groups For example, DQ2 = alleles that start with DQB1*02 (*0201, *0202, and *0203).

DQ2 is encoded by alleles that start with DQB1*02

DQ4 is encoded by alleles that start with DQB1*04

There are two exceptions worth noting:

DQ1 is 'split' into DQ5 and DQ6, in this case the DQB1 alleles start with

-DQ5 encoded by alleles that start with DQB1*05

-DQ6 encoded by alleles that start with DQB1*06

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

-DQ7 = DQB1*0301 (or very similar alleles)

-DQ8 = DQB1*0302 (or very similar alleles)

-DQ9 = DQB1*0303 (or very similar alleles)

You are DQ6 and DQ7.

thank you for posting that.

Does anyone know of an good book that explains all this., or is it bestjust to do all my seaching online

paula

Nancym Enthusiast

HLA-DQB1 Molecular analysis, Allele 1 0302 (DQ8 -- Celiac)

HLA-DQB1 Molecular analysis, Allele 1 0501 (DQ1 -- Gluten Sensitivity Dr. Hadjivasilliou finds this one in brain related gluten issues)

AndreaB Contributor

Mine: HLA-DQ 2,3 (subtype 2,7) or DQ2 and DQ7

Husband: HLA-DQ 2,3 (subtype 2,8) or DQ2 and DQ8

Daughter:HLA-DQ 3,3 (subtype 8,7) or DQ8 and DQ7

Son: HLA-DQ 2,2 (subtype 2,2) or Double DQ2

Son: Haven't gene tested yet but DQ2, 7 or 8 are the only possibilities.

happygirl Collaborator
thank you for posting that.

Does anyone know of an good book that explains all this., or is it bestjust to do all my seaching online

paula

Paula,

You are welcome :).

I've found the best info online. go to wikipedia, and search for hla dq2, and click on the first link...I think its a great comprehensive overview of the hla dq genes of interest to us.

confused Community Regular

Thanks for that info. Yesterday i just kept typing in the difference between 7 and 8, i didnt hink to type just in 7 lol. I am going to try and do some more research today. I even emailed enterolab to see what they will tell me, I am sure i wont hear from them til next week tho.

paula

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