Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Can Everyone Post Their Genes

confused

Recommended Posts

confused Community Regular
confused
Posted

Ok I have been intrigued with the celiac and gluten genes. So i was hoping everyone can post their genes.

paula

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


confused Community Regular
confused
Posted
  • Author

Here are mine

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

confused Community Regular
confused
Posted
  • Author

my step-sons are

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 2,1 (Subtype 2,6)

Lisa Mentor
Lisa
Posted

I like Gloria Vanderbilt...oh genes. Don't know mine, a biopsy sealed it for me. ;)

Teacher1958 Apprentice
Teacher1958
Posted
Ok I have been intrigued with the celiac and gluten genes. So i was hoping everyone can post their genes.

paula

Oh my gosh! Do you guys actually know what all that means? If I have this test done eventually, will someone interpret it for me? Yikes!

mftnchn Explorer
mftnchn
Posted

Here's mine:

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0201

Serologic equivalent: HLA-DQ 2,2 (Subtype 2,2)

dally099 Contributor
dally099
Posted
Here's mine:

HLA-DQB1 Molecular analysis, Allele 1 0201

HLA-DQB1 Molecular analysis, Allele 2 0201

Serologic equivalent: HLA-DQ 2,2 (Subtype 2,2)

heres mine: dont ask me what they mean though,

HLA-DQB1 Molecular analysis, allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0502

Serologic equivalent: HLA-DQ 3,1 (subtype 8,5)

hey if anyone knows what the heck this all means would love to here it. thanks nadine

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


GeoffCJ Enthusiast
GeoffCJ
Posted

Today - Old Navy.

Normally - Levis

But I'm working on switching the wardrobe to organic cotton.

I don't know my Gene's despite paying for the test from Enterolab. I'd have to look. I was diagnosed both by biopsy, diet, and Enterolab. Having had so many wrong diagnosis-es over the years, there was really no way I was going to let any one test change my life. All three pretty much confirmed each other, and that sealed the deal.

Geoff

dlp252 Apprentice
dlp252
Posted

Mine are in my signature because I can never remember what they are.

holiday16 Enthusiast
holiday16
Posted

I never had the gene test done so I only know from deduction what mine are since my parents had theirs done. My mother's was:

HLA-DQB1 Molecular analysis, Allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0501

Serologic equivalent: HLA-DQ 3,1 (Subtype 8,5)

and my dad's was:

Serologic equivalent: HLA-DQ 3,3 (Subtype 7,7)

Since my dad has a double gene I know I have the 7 and then either an 8 or 5 from my mother. Interestingly enough even though it's my mother that has the celiac gene it was my dad that tested positive for gluten intolerance. My brother is postive as well and he has the 7 and 8 genes.

burdee Enthusiast
burdee
Posted

Here's my Enterolab gene test results. Everyone who tests with Elab will get an explanation of their genetic (and other test) results. I also posted the interpretation included in my Elab gene test results:

Gene Test for Gluten Sensitivity

Molecular Analysis: HLA-DQB1*0602, 0302

Serologic equivalent: HLA-DQ 1,3 (subtype 6,8)

HLA gene analysis reveals that you have a copy of one of the main genes that predisposes to gluten sensitivity and celiac sprue, HLA-DQ3, subtype 8 (HLA-DQ8). This genotype also can predispose to microscopic colitis and other autoimmune syndromes.

BURDEE

happygirl Collaborator
happygirl
Posted

HLA DQ8

Nantzie Collaborator
Nantzie
Posted

Mine:

HLA-DQB1*0602, 0609

Daughter's:

HLA-DQB1*0609, 0301

Son's:

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

..........................

Husband hasn't had his done, but he obviously has at least one copy of HLA-DQB1 Molecular analysis, Allele 1 0301 .

Nancy

confused Community Regular
confused
Posted
  • Author

Thanks everyone that posted. I had some thoughts going threw my head yesterday and wanted to compare gene types, and see who had genes like mine. Plus i want to do some research on gene types sometime in the near future. I have to much going on right now to think straight, but it is on my 2 to list lol

paula

jerseyangel Proficient
jerseyangel
Posted
Mine are in my signature because I can never remember what they are.

:D Mine, too!

happygirl Collaborator
happygirl
Posted
heres mine: dont ask me what they mean though,

HLA-DQB1 Molecular analysis, allele 1 0302

HLA-DQB1 Molecular analysis, Allele 2 0502

Serologic equivalent: HLA-DQ 3,1 (subtype 8,5)

hey if anyone knows what the heck this all means would love to here it. thanks nadine

Your HLA DQ 3 subtype 8 is what is referred to as HLA DQ 8, which is a Celiac gene.

from wikipedia:

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

DQ7 = DQB1*0301 (or very similar alleles)

DQ8 = DQB1*0302 (or very similar alleles)

DQ9 = DQB1*0303 (or very similar alleles)

pedro Explorer
pedro
Posted

Hi

Please below my name. You will find them.

confused Community Regular
confused
Posted
  • Author
Your HLA DQ 3 subtype 8 is what is referred to as HLA DQ 8, which is a Celiac gene.

from wikipedia:

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

DQ7 = DQB1*0301 (or very similar alleles)

DQ8 = DQB1*0302 (or very similar alleles)

DQ9 = DQB1*0303 (or very similar alleles)

See this is one of the things that i am really interested in. I am dqb1 0301, which i think is very close to dqb1 0302. I am not sure how close they are but would really like to find out.

paula

happygirl Collaborator
happygirl
Posted
Here are mine

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

close doesn't mean the same though.

the entire explanation, from wikipedia:

Note on DQ Serotype Names in Relationship with Allele Names

DQ serotypes are usually a recognition of Beta chain isoform groups For example, DQ2 = alleles that start with DQB1*02 (*0201, *0202, and *0203).

DQ2 is encoded by alleles that start with DQB1*02

DQ4 is encoded by alleles that start with DQB1*04

There are two exceptions worth noting:

DQ1 is 'split' into DQ5 and DQ6, in this case the DQB1 alleles start with

-DQ5 encoded by alleles that start with DQB1*05

-DQ6 encoded by alleles that start with DQB1*06

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

-DQ7 = DQB1*0301 (or very similar alleles)

-DQ8 = DQB1*0302 (or very similar alleles)

-DQ9 = DQB1*0303 (or very similar alleles)

You are DQ6 and DQ7.

SUZ42 Explorer
SUZ42
Posted

DQ 3 (7)

DQ 3 (8)

confused Community Regular
confused
Posted
  • Author
close doesn't mean the same though.

the entire explanation, from wikipedia:

Note on DQ Serotype Names in Relationship with Allele Names

DQ serotypes are usually a recognition of Beta chain isoform groups For example, DQ2 = alleles that start with DQB1*02 (*0201, *0202, and *0203).

DQ2 is encoded by alleles that start with DQB1*02

DQ4 is encoded by alleles that start with DQB1*04

There are two exceptions worth noting:

DQ1 is 'split' into DQ5 and DQ6, in this case the DQB1 alleles start with

-DQ5 encoded by alleles that start with DQB1*05

-DQ6 encoded by alleles that start with DQB1*06

DQ3 is split into DQ7, DQ8, and DQ9, but allele retain DQB1*03.

-DQ7 = DQB1*0301 (or very similar alleles)

-DQ8 = DQB1*0302 (or very similar alleles)

-DQ9 = DQB1*0303 (or very similar alleles)

You are DQ6 and DQ7.

thank you for posting that.

Does anyone know of an good book that explains all this., or is it bestjust to do all my seaching online

paula

Nancym Enthusiast
Nancym
Posted

HLA-DQB1 Molecular analysis, Allele 1 0302 (DQ8 -- Celiac)

HLA-DQB1 Molecular analysis, Allele 1 0501 (DQ1 -- Gluten Sensitivity Dr. Hadjivasilliou finds this one in brain related gluten issues)

AndreaB Contributor
AndreaB
Posted

Mine: HLA-DQ 2,3 (subtype 2,7) or DQ2 and DQ7

Husband: HLA-DQ 2,3 (subtype 2,8) or DQ2 and DQ8

Daughter:HLA-DQ 3,3 (subtype 8,7) or DQ8 and DQ7

Son: HLA-DQ 2,2 (subtype 2,2) or Double DQ2

Son: Haven't gene tested yet but DQ2, 7 or 8 are the only possibilities.

happygirl Collaborator
happygirl
Posted
thank you for posting that.

Does anyone know of an good book that explains all this., or is it bestjust to do all my seaching online

paula

Paula,

You are welcome :).

I've found the best info online. go to wikipedia, and search for hla dq2, and click on the first link...I think its a great comprehensive overview of the hla dq genes of interest to us.

confused Community Regular
confused
Posted
  • Author

Thanks for that info. Yesterday i just kept typing in the difference between 7 and 8, i didnt hink to type just in 7 lol. I am going to try and do some more research today. I even emailed enterolab to see what they will tell me, I am sure i wont hear from them til next week tho.

paula

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,730
    • Most Online (within 30 mins)
      7,748
    Sumac
    Newest Member
    Sumac
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Theresa2407
      How Come Gluten Didnt Bother Me In Italy

      By Theresa2407 · Posted

      Maybe you have a low  intolerance to Wheat.   Rye, Barley and Malt are the gluten in Celiac disease.  It has always been stated Wheat and Gluten, not just a Wheat intolerance.  Barley will keep me in bed for (2) weeks.  Gut, Migrains, Brain fog, Diahrea.  It is miserable.  And when I was a toddler the doctor would give me a malt medicine because I always had Anemia and did not grow.  Boy was he off.  But at that time the US didn't know anyone about Celiac.  This was the 1940s and 50s.  I had my first episode at 9 months and did not get a diagnosis until I was 50.  My immune system was so shot before being diagnoised, so now I live with the consequences of it. I was so upset when Manufacturers didn't want to label their products so they added barley to the product.  It was mostly the cereal industry.  3 of my favorite cereals were excluded because of this. Malt gives me a bad Gut reaction.
    • Gigi2025
      How Come Gluten Didnt Bother Me In Italy

      By Gigi2025 · Posted

      Thanks much Scott.  Well said, and heeded.   I don't have Celiac, which is fortunate.
    • Scott Adams
      Possible celiac - need advice

      By Scott Adams · Posted

      Do you have the results of your endoscopy? Did you do a celiac disease blood panel before that?  Here is more info about how to do a gluten challenge for a celiac disease blood panel, or for an endoscopy: and this recent study recommends 4-6 slices of wheat bread per day:    
    • Scott Adams
      Celiac or not??

      By Scott Adams · Posted

      It is odd that your Tissue Transglutaminase (TTG) IgA level has bounced from the "inconclusive" range (7.9, 9.8) down to a negative level (5.3), only to climb back up near the positive threshold. This inconsistency, coupled with your ongoing symptoms of malabsorption and specific nutrient deficiencies, is a strong clinical indicator that warrants a more thorough investigation than a simple "satisfactory" sign-off. A negative blood test does not definitively rule out celiac disease, especially with such variable numbers and a classic symptomatic picture. You are absolutely right to seek a second opinion and push for a referral to a gastroenterologist. A biopsy remains the gold standard for a reason, and advocating for one is the most direct path to getting the answers you need to finally address the root cause of your suffering. Here is more info about how to do a gluten challenge for a celiac disease blood panel, or for an endoscopy: and this recent study recommends 4-6 slices of wheat bread per day:    
    • Scott Adams
      How Come Gluten Didnt Bother Me In Italy

      By Scott Adams · Posted

      There is a distinction between gluten itself and the other chemicals and processing methods involved in modern food production. Your experience in Italy and Greece, contrasted with your reactions in the U.S., provides powerful anecdotal evidence that the problem, for some people, may not be the wheat, but the additives like potassium bromate and the industrial processing it undergoes here. The point about bromines displacing iodine and disrupting thyroid function is a significant one, explaining a potential biological mechanism for why such additives could cause systemic health issues that mimic gluten sensitivity. It's both alarming and insightful to consider that the very "watchdog" agencies meant to protect us are allowing practices banned in many other developed countries. Seeking out European flour and your caution about the high-carb, potentially diabeticgenic nature of many gluten-free products are excellent practical takeaways from your research, but I just want to mention--if you have celiac disease you need to avoid all wheat, including all wheat and gluten in Europe.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.