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Celiac cure


yashkanthale

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yashkanthale Newbie

Hello, This is Yash Kanthale, From India, Maharashtra. (Celiac Patient)

I herd that there is some research going on treatment of celiac decease and also the clinical trials is at phase 2 level and they have found the treatment which can reverse the celiac decease. The research is in the link below:

https://www.sciencedaily.com/releases/2019/10/191022080723.htm

And also Research on CNP-101 And TAK-101 Medicine and let me know.

I want to ask that is it true that when final phase is done we can treat celiac decease and can actually reverse the celiac decease, please let me know after your research on this article. Thank you!!


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trents Grand Master
(edited)

"After treatment with the technology, the patients were able to eat gluten with a substantial reduction in inflammation . . . Celiac patients treated with the COUR nanoparticle, CNP-101, showed 90% less immune inflammation response than untreated patients. By stopping the inflammatory response, CNP-101 showed the capacity to protect the intestines from gluten related injury."

Let's be clear. The researchers connected with this project are not saying it eliminates the need to eat gluten-free. But this has great promise for protecting against damage from cross-contamination/incidental types of gluten exposures where the amount of gluten consumed is minor. And most of us would be very happy with that if it turns out to hold true after all the testing is done. How many phases are there to these kind of trials anyway?

Of course, the worry I have here is that many Celiacs would let their guard down and cheat too often in their gluten-free living.

Edited by trents
Posterboy Mentor

Yash,

Being from India your over reliance on Rice might be causing you to have low Thiamine levels where Beri Beri is still common.

I like your research but it doesn't answer the question of persistent inflammation outside the GI track and through the whole body.

See this research that shows how taking Baking Soda might help with that....it explains well how our body goes into inflammation mode when we get low in Acetylcholine...

https://www.medicalnewstoday.com/articles/321624

And someone who has developed Beri Beri would be low in Acetylcholine....

Here is a nice article about how Acteylcholine is used by the body to regulate it's functions through out the body...

https://www.peirsoncenter.com/articles/acetylcholine-how-and-why-to-optimize-the-synthesis-of-this-vital-neurotransmitter

And being low in Thiamine can lead to thin Villi in mammals.  Try taking some Benfotiamine to see if it helps you fell better......It should help most of your fatigue issues.....if you are having any yet?

Also see this posterboy blog post that discusses how Thiamine supplementation can be used by Celiac's.

I hope this is helpful but it is not medical advise.

Posterboy,

trents Grand Master

I realize we are straying a bit off topic but rice can also be high in arsenic. Where arsenic is present in the soil, rice is naturally good at taking it up.

knitty kitty Grand Master

Thiamine is a known chelator of arsenic and other heavy metals like lead.  Thiamine in the form of TTFD is used...

https://europepmc.org/article/med/12195231

https://www.hormonesmatter.com/chelation-therapy-medicine/

 

DJFL77I Experienced

but how far away is it from actually being fda approved?  50 years?

DJFL77I Experienced

https://wbbm780.radio.com/articles/nu-finds-new-treatment-may-reverse-celiac-disease

In an industrial collaboration project, TU Wien has developed a medication that can alleviate or even completely eliminate the symptoms of celiac disease. It should be available as early as 2021. Celiac disease is a fairly common disease, affecting one to two percent of the European population.

https://medicalxpress.com/news/2018-09-remedy-celiac-disease.html


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DJFL77I Experienced
yashkanthale Newbie
1 hour ago, DJFL77I said:

but how far away is it from actually being fda approved?  50 years?

I don't know but soon.. 

yashkanthale Newbie

 

I don't know but soon.. 

yashkanthale Newbie
1 hour ago, DJFL77I said:

https://wbbm780.radio.com/articles/nu-finds-new-treatment-may-reverse-celiac-disease

In an industrial collaboration project, TU Wien has developed a medication that can alleviate or even completely eliminate the symptoms of celiac disease. It should be available as early as 2021. Celiac disease is a fairly common disease, affecting one to two percent of the European population.

https://medicalxpress.com/news/2018-09-remedy-celiac-disease.html

I hope and excited to hear that and also iam waiting for that thanks for sharing!!!!

DJFL77I Experienced

https://www.beyondceliac.org/research-news/drug-to-treat-celiac-disease-gets-to-furthest-ever-stage-of-study/

Innovate Biopharmaceuticals today announced that is has given the first dose of larazotide acetate to a study participant. Larazotide acetate is the first celiac disease drug to get to a critical, large-scale Phase 3 clinical trial.

Phase 3:  The stage of clinical trial in which researchers demonstrate whether a drug offers a treatment benefit to a specific population. This phase involves 300 to 3,000 volunteers who have the disease or condition and typically lasts one to four years. It is part of the Food and Drug Administration approval process.

trents Grand Master
(edited)

It should be cautioned that neither of these two articles claim to completely eliminate the need to eat gluten free. Both seem to target incidental gluten exposure such as we get from cross contamination. Here's a quote from the first article:

"Northwestern claims after celiac patients were treated with the technology, they were able to eat gluten and experience far less inflammation. The results also show a trend toward protecting patients’ small intestine from gluten exposure."

Notice it says, "far less inflamation". 

And from the second linked article: ""It remains to be seen whether the symptoms will disappear completely or will only be alleviated. The precise effects will probably vary from person to person."

Edited by trents

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    • trents
      Welcome to the celiac.com communiuty, @Matthias! Yes, we have been aware that this can be an issue with mushrooms but as long as they are rinsed thoroughly it should not be a problem since the mushrooms don't actually incorporate the gluten into their cellular structure. For the same reason, one needs to be careful when buying aged cheeses and products containing yeast because of the fact that they are sometimes cultured on gluten-containing substrate.
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      The one kind of food I had been buying and eating without any worry for hidden gluten were unprocessed veggies. Well, yesterday I discovered yet another pitfall: cultivated mushrooms. I tried some new ones, Shimeji to be precise (used in many asian soup and rice dishes). Later, at home, I was taking a closer look at the product: the mushrooms were growing from a visible layer of shredded cereals that had not been removed. After a quick web research I learned that these mushrooms are commonly cultivated on a cereal-based medium like wheat bran. I hope that info his helpful to someone.
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