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- Scott Adams replied to Fabrizio's topic in Related Issues & Disorders10Kan-101
Another one bites the dust! Oh well... -
- Shelley22 replied to Fabrizio's topic in Related Issues & Disorders10Kan-101
KAN-101 may be dead: https://www.reddit.com/r/Celiac/comments/1mnd628/kan101_is_dead_in_the_water_i_believe/- 1
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- Scott Adams replied to Kirita's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms3
Help with genetic testing
The genetic testing results you provided indicate that your child carries two copies of the HLA-DQ2.5 beta chain (DQ Beta 1 *02:01, *02:01), which is a high-risk genetic marker for celiac disease. However, the alpha chain (DQ Alpha 1 *05:01, *05) is only partially present, as HLA-DQ2.5 typically requires the alpha chain *05:01 paired with the beta chain ...- 1
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By Scott Adams · Posted
The genetic testing results you provided indicate that your child carries two copies of the HLA-DQ2.5 beta chain (DQ Beta 1 *02:01, *02:01), which is a high-risk genetic marker for celiac disease. However, the alpha chain (DQ Alpha 1 *05:01, *05) is only partially present, as HLA-DQ2.5 typically requires the alpha chain *05:01 paired with the beta chain 02:01. Since your child has two copies of the beta chain (02:01) but only one full *05:01 alpha allele (the other appears truncated as *05), this suggests they are heterozygous for HLA-DQ2.5 rather than homozygous. The term "permissive for celiac disease" means your child has genetic susceptibility but not necessarily the highest-risk genotype (homozygous DQ2.5). Since celiac disease development also depends on environmental triggers and other factors, further testing (such as antibody screening or biopsy) may be needed to confirm a diagnosis. Consulting a genetic counselor or gastroenterologist can help clarify these results and next steps. -
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As my doctor said, you don't have to eat breakfast food for breakfast. I may have a leftover piece of chicken and left over squash or eggs or I am actually more likely to skip breakfast as I do intermittent fasting. In that case I eat lunch around 11:30 and have some guacamole and a salad with chicken or tuna. For dinner I have pork, shrimp, chicken, lamb, or turkey with half a baked sweet potato and some broccoli, green beans, beets, carrots or cauliflower. I do not eat any grains on the advice of my doctor. I do not eat commercially processed products, even if they say they are gluten-free. I make Warrior Bread every few weeks. It has no yeast and contains almond flour and dried sweet potato. Very tasty too. A good book to help in this regard is No Grain, No Pain by Peter Osborne. Thankfully, I can eat coconut and nuts and use those flours in baking and also use nut milks in cooking. Since I am allergic to chocolate and vanilla, lemon is my go to flavor for something sweet. My migraines totally disappeared once I went gluten and casein free. I can occasionally eat certain high fat cheeses that are low in casein, as well as grass fed butter. I use lots of Organic Olive and Avocado oil. The problems I thought I had with nightshades went away when I went fully organic. And, the rest of my issues went away by avoiding the foods I tested positive to as well as avoiding all grains. I will be the first one to say that it is a very expensive way of eating, but thankfully we can afford to eat that way. The good news is that I take no prescription meds at age 72. At 54 before diagnosis, I was a mess and on a boatload of pharmaceuticals.
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