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- Wheatwacked commented on Nicky2925NZ's blog entry in Nicky2025BZ2GLUTEN EASE TABLETS DONT WORK
"Vitamin D, as an immune modulator, is known to regulate immune response and maybe implicated in disease pathogenesis or susceptibility of celiac disease. Components of the immune system, such as B-lymphocytes, T-lymphocytes, and dendritic cells, are influenced by the regulatory effects of Vitamin D ... Increasing evidence also suggests that Vitamin D deficiency... -
- Scott Adams replied to Zuma888's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease10Hypothetical question about antibodies
Great question! Even if some individuals with celiac disease don’t experience immediate villi damage from occasional cross-contamination, it’s still strongly recommended to maintain strict avoidance of gluten. The immune response triggered by gluten can vary between individuals, and even small amounts may cause systemic inflammation or other symptoms, ev...- 1
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- Zuma888 commented on Jefferson Adams's article in Diagnosis, Testing & Treatment26How Refining the Gluten Challenge May Help Improve Diagnostics for Celiac Disease
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- knitty kitty commented on Jefferson Adams's article in Diagnosis, Testing & Treatment26How Refining the Gluten Challenge May Help Improve Diagnostics for Celiac Disease
I'm fine as long as I stay away from gluten. My Celiac went undiagnosed for too long and I accumulated health problems. If I can help others on their journey, everything has been worthwhile.- 1
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By Scott Adams · Posted
Great question! Even if some individuals with celiac disease don’t experience immediate villi damage from occasional cross-contamination, it’s still strongly recommended to maintain strict avoidance of gluten. The immune response triggered by gluten can vary between individuals, and even small amounts may cause systemic inflammation or other symptoms, even if intestinal damage isn’t immediately detectable. Additionally, repeated exposure—even at low levels—could lead to cumulative harm over time. Strict avoidance of cross-contamination remains the safest approach to prevent long-term complications and ensure overall health. Everyone’s sensitivity differs, so working with a healthcare provider to tailor precautions is ideal. -
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By knitty kitty · Posted
You have one gene for Celiac. You have a second autoimmune disease, Hashimoto's thyroiditis, which is frequently found at a higher rate with Celiac. HLA genes carry autoimmune disease genes like Celiac and Hashimoto's and diabetes and others. You have Celiac symptoms of reacting after gluten. You said "I am however still suffering from the effects of the gluten challenge (food sensitivities, slight brain fog, weird stool, fatigue, swollen thyroid, bodyaches)." And your anti-thyroid antibodies increase after gluten exposure. While tTg IgA does not directly attack the thyroid, gluten exposure does trigger the immune system to produce antibodies against the thyroid in genetically predisposed individuals. You did not eat sufficient gluten (10 grams of gluten per day for two weeks minimum) to raise the autoimmune antibodies to the point they can be measured in the blood, so your blood tests may well be inaccurate. You could choose to continue the gluten challenge of 10 grams a day for at least two weeks and get retested. At the very least, you know that gluten is harmful to your thyroid, and because you are genetically predisposed to Celiac disease, a strict gluten free diet would be beneficial for your overall health. -
Thanks @Scott Adams! I guess my question now is: do the celiacs who can get away with regular contamination without villi damage as you mentioned have to be strict about cross-contamination ?
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Thank you very much @knitty kitty! I'm glad you brought up the point about histamine. I have been taking an antihistamine after meals where I don't feel so good and never knew why it helped so much. At first I thought I might have a food allergy, but I recently did a food allergy test and I actually have ZERO food allergies. Regarding your last point about the stages of grief, are you saying it's likely that I have celiac? I have Hashimoto's BTW and I know for sure that gluten causes an autoimmune response to my thyroid as my anti-TPO and anti-Tg go up and my throat feels swollen. Could the symptoms be due to that autoimmune response?
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